Recombinant Rabbit Anti-SOX10 Antibody (clone R09-7D8) (CAT#: VS3-FY1374)
This product is a recombinant rabbit antibody that recognizes SOX10. This antibody has been reported for use in Western Blot. The clone R09-7D8 is specific for human, rat SOX10. The antigen is human sox10 synthetic peptide.
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WB
Figure 1. Recombinant Rabbit Anti-SOX10 Antibody (clone R09-7D8) in WB.
Western Blot analysis of SOX10 in rat brain, C6, HeLa lysates using SOX10 Antibody.
Specifications
- Immunogen
- Human SOX10 synthetic peptide.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Rat SOX10
- Species Reactivity
- Human, Rat
- Clone
- R09-7D8
- Applications
- Western Blot
- Conjugate
- Unconjugated
- MW
- Calculated MW: 50 kDa; Observed MW: 62 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- SRY-Box 10; Dominant Megacolon, Mouse, Human Homolog Of; SRY (Sex Determining Region Y)-Box 10; SRY-Related HMG-Box Gene 10; Transcription Factor SOX-10; SRY Box 10
- Gene ID
- 6663
- UniProt ID
- P56693
- Cellular Localization
- Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus
- Protein Refseq
- NP_008872.1
- Function
- Transcription factor that plays a central role in developing and mature glia (By similarity).
Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity).
Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity).
Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087).
Transcriptional activator of MBP, via binding to the gene promoter (By similarity).
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3374 | Hi-Affi™ Recombinant Rabbit Anti-SOX10 Monoclonal Antibody (DS3374AB) | WB, ICC | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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