Recombinant Anti-SYP Vesicular Antibody, EV Displayed (VS-0425-YC136)
CAT#: VS-0425-YC136
The Recombinant Anti-SYP Vesicular Antibody, EV Displayed (VS-0425-YC136) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SYP-expressed cells or tissues. The SYP is an integral membrane protein of small synaptic vesicles, associated with an X-linked form of cognitive disability through mutations.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/55505/125080_B_8_5.jpg
Normal Tissue
Figure 2 Duodenum
Goblet cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Paneth cells
Staining: High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/55505/125080_A_9_2.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (K-562, SCLC-21H, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000102003-SYP/subcellular
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- SYP
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Synaptophysin
- Introduction
- This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability.
- Alternative Names
- MRX96
- Gene ID
- 6855
- UniProt ID
- P08247
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SYP"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1588z | Mouse Anti-SYP Recombinant Antibody (clone 23G4) | WB, IP | Mouse IgM, κ |
| ZG-0377U | Rabbit Anti-SYP Recombinant Antibody (clone Q21-Q) | IHC-P | Rabbit IgG |
| VS3-CJ492 | Mouse Anti-SYP Recombinant Antibody (clone ABT-SYN) | IHC-P | Mouse IgG2a, κ |
| VS3-FY1420 | Recombinant Mouse Anti-SYP Antibody (clone 3E3-1E6-3E10) | IHC-P | Mouse IgG2a |
| VS3-FY1421 | Recombinant Rabbit Anti-SYP Antibody (clone R06-2A2) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-494CT | Anti-Human Synaptophysin Recombinant Antibody (C1-3) | ELISA, FC | Human antibody |
| TAB-494CT-S(P) | Anti-Human Synaptophysin Recombinant Antibody scFv Fragment (C1-3) | ELISA, FC | Human antibody |
| TAB-494CT-F(E) | Anti-Human Synaptophysin Recombinant Antibody Fab Fragment (C1-3) | ELISA, FC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3483 | Hi-Affi™ Recombinant Rabbit Anti-SYP Monoclonal Antibody (DS3483AB) | IHC-FoFr, IHC-P, WB | IgG |
| MOR-4514 | Hi-Affi™ Recombinant Rabbit Anti-SYP Monoclonal Antibody (TH22DS) | WB, IF, ICC, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1544CQ | Mouse Anti-SYP Recombinant Antibody (clone SP15) | WB, ELISA, IHC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7053 | Anti-SYP Immunohistochemistry Kit | IHC | |
| VS-0525-XY7054 | Anti-Rat SYP Immunohistochemistry Kit | IHC | |
| VS-0525-XY7055 | Anti-Mouse SYP Immunohistochemistry Kit | IHC |
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