Recombinant Anti-SYVN1 Vesicular Antibody, EV Displayed (VS-0425-YC613) (CAT#: VS-0425-YC613)

The Recombinant Anti-SYVN1 Vesicular Antibody, EV Displayed (VS-0425-YC613) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to SYVN1-expressed cells or tissues. SYVN1 is a protein involved in ER-associated degradation, removing unfolded proteins via ubiquitin-proteasome pathways.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Recombinant Antibody

  • Application
  • ELISA, FC, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • SYVN1
  • Host Animal
  • Mouse
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • Protein A
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Synoviolin 1
  • Biological Process
  • Stress response, Ubl conjugation pathway
  • Molecular Function
  • Transferase
  • Cellular Localization
  • Nucleoplasm, Endoplasmic reticulum, Plasma membrane
  • Introduction
  • This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins.
  • Alternative Names
  • DER3, HRD1

Downloads

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