Recombinant Anti-TCIRG1 Vesicular Antibody, EV Displayed (VS-0425-YC578)
CAT#: VS-0425-YC578
The Recombinant Anti-TCIRG1 Vesicular Antibody, EV Displayed (VS-0425-YC578) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TCIRG1-expressed cells or tissues. TCIRG1 is a subunit of the vacuolar H±ATPase (V-ATPase) complex, vital for pH regulation in cells. It aids in intracellular processes like protein sorting and receptor-mediated endocytosis, with mutations linked to infantile malignant osteopetrosis.








Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TCIRG1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- T cell immune regulator 1, ATPase H+ transporting V0 subunit a3
- Biological Process
- Hydrogen ion transport, Ion transport, Transport
- Cellular Localization
- Mitochondria
- Introduction
- This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq, May 2017]
- Alternative Names
- a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7
- Gene ID
- 10312
- UniProt ID
- Q13488
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Datasheet
MSDS
COA
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See other products for "TCIRG1"
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-3563z | Mouse Anti-TCIRG1 Recombinant Antibody (MOB-3563z) | WB, IP, ELISA | Mouse IgG2a, κ |
MOB-1912MZ | Recombinant Mouse Anti-Human TCIRG1 Antibody (clone 6H3) | WB | Mouse antibody |
HPAB-0340-WJ | Human Anti-TCIRG1 Recombinant Antibody (clone Metiliximab) | ELISA | Humanized IgG1, κ |
HPAB-0341-WJ | Human Anti-TCIRG1 Recombinant Antibody (clone Neliximab) | ELISA | Humanized IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-3563z-F(E) | Recombinant Anti-Human TCIRG1 Antibody Fab Fragment | IF, Neut, FuncS | Fab |
HPAB-0340-WJ-F(E) | Human Anti-TCIRG1 Recombinant Antibody (clone Metiliximab); Fab Fragment | ELISA | Humanized Fab |
HPAB-0341-WJ-F(E) | Human Anti-TCIRG1 Recombinant Antibody (clone Neliximab); Fab Fragment | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-3563z-S(P) | Recombinant Anti-Human TCIRG1 Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
HPAB-0340-WJ-S(P) | Human Anti-TCIRG1 Recombinant Antibody (clone Metiliximab); scFv Fragment | ELISA | Humanized scFv |
HPAB-0341-WJ-S(P) | Human Anti-TCIRG1 Recombinant Antibody (clone Neliximab); scFv Fragment | ELISA | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-XY7142 | Anti-TCIRG1 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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