Recombinant Mouse Anti-TCL1A Antibody (clone 4A1-8E8-2F9)
CAT#: VS3-FY1433
This product is a recombinant mouse antibody that recognizes TCL1A. This antibody has been reported for use in Immunohistochemistry-Paraffin. The clone 4A1-8E8-2F9 is specific for human TCL1A. The antigen is synthetic peptide derived from human tcl1.
Gene Expression
Tested Data
Subcellular Location
Figure 1 IF staining of human cell line REH
Immunofluorescent staining of human cell line REH shows localization to nucleoplasm, cytosol & endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/1778_H1_6_selected.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/37654_A_9_8.jpg
Normal Tissue
Figure 3 Tonsil
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/37654_A_4_8.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (Daudi, REH, U-698)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100721-TCL1A
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IHC-P
Figure 1. Recombinant Mouse Anti-TCL1A Antibody (clone 4A1-8E8-2F9) in IHC-P.
Immunohistochemical analysis of paraffin-embedded tonsil using T-cell leukemia/lymphoma protein 1A antibody. High pressure and high temperature sodium citrate pH 6.0 for antigen retrieval.
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Specifications
- Immunogen
- Synthetic peptide derived from human TCL1.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human TCL1A
- Species Reactivity
- Human
- Clone
- 4A1-8E8-2F9
- Applications
- Immunohistochemistry-Paraffin
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS, pH 7.3, 50% glycerol, 0.5% BSA
- Preservative
- 0.02% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry-Paraffin: 1/100-1/500
Target
- Alternative Names
- T Cell Leukemia/Lymphoma 1A; T-Cell Leukemia/Lymphoma 1A; Protein P14 TCL1; Oncogene TCL-1; Oncogene TCL1; TCL1; T-Cell Leukemia/Lymphoma Protein 1A; T-Cell Lymphoma-1
- Gene ID
- 8115
- UniProt ID
- P56279
- Sequence Similarities
- Belongs to the TCL1 family.
- Cellular Localization
- Cytoplasm, Endoplasmic reticulum, Microsome, Nucleus
- Protein Refseq
- NP_001092195.1; NP_068801.1
- Function
- Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
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Isotype Control
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Reconstitution Buffer
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Recommended Dilution Buffer
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See other products for "TCL1A"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1913MZ | Recombinant Mouse Anti-Human TCL1A Antibody (clone 2-32) | FC, IHC-P, IP, WB | Mouse antibody |
| ZG-0112C | Mouse Anti-TCL1A Recombinant Antibody (clone ABT-TCL1) | IHC-P, IF | Mouse IgG |
| ZG-0113C | Mouse Anti-TCL1A Recombinant Antibody (clone PT0243) | IHC-P, IF | Mouse IgG |
| VS3-QX1088 | Mouse Anti-TCL1A Recombinant Antibody (clone 5E-3A) | WB, FC | Mouse IgG1 |
| VS7-0425-WR959 | Mouse Anti-TCL1A Recombinant Antibody (clone 2E3A5) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0576MZ | Chicken Anti-TCL1A Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3524 | Rabbit Anti-TCL1A Recombinant Antibody (clone DS3524AB) | FC, ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0167 | APC-A*02:01/Human TCL1 (LLPIMWQL) MHC Tetramer | FCM | |
| MHC-CN0168 | PE-A*02:01/Human TCL1 (LLPIMWQL) MHC Tetramer | FCM | |
| MHC-CN1427 | PE-A*02:01/Human TCL1A (SLLPIMWQL) MHC Tetramer | FCM | |
| MHC-YF289 | A*02:01/Human TCL1 (SLLPIMWQL) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY204 | CytoStream™ Mouse Anti-TCL1A Recombinant Antibody (VS-0225-XY204) | FC, IF, IHC | Mouse IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2260 | Anti-TCL1A Immunohistochemistry Kit | IHC | |
| VS-0525-XY7143 | Anti-Human TCL1A Immunohistochemistry Kit | IHC |
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