Recombinant Anti-TFRC Vesicular Antibody, EV Displayed (VS-0425-YC571)
CAT#: VS-0425-YC571
The Recombinant Anti-TFRC Vesicular Antibody, EV Displayed (VS-0425-YC571) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TFRC-expressed cells or tissues. TFRC is a receptor for iron uptake, necessary for erythropoiesis and neurologic development.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to endosomes & lysosomes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28598/546_F8_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/207_B2_1_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/208_B2_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_8_3.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Pachytene spermatocytes
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_6_6.jpg
Normal Tissue
Figure 7 Bone marrow
Hematopoietic cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_B_6_4.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
Cell lines ordered by descending RNA expression order.
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000072274-TFRC
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TFRC
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Cynomolgus
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Transferrin receptor
- Biological Process
- Endocytosis, Host-virus interaction
- Molecular Function
- Host cell receptor for virus entry, Receptor, Transducer
- Cellular Localization
- Endosomes, Lysosomes
- Introduction
- This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
- Alternative Names
- CD71, p90, TFR1
- Gene ID
- 7037
- UniProt ID
- P02786
REVIEWS AND Q&AS
CITATIONS
RESOURCES
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G067E | Anti-TFRC immunotoxin HB21 (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G067D | Anti-TFRC immunotoxin HB21 (scFv)-DT | Cytotoxicity assay, Function study | |
| AGTO-G067G | Anti-TFRC immunotoxin HB21 (scFv)-Gel | Cytotoxicity assay, Function study | |
| AGTO-L076E | transferrin-PE immunotoxin | Cytotoxicity assay, Functional assay | |
| AGTO-L076R | transferrin-RTA immunotoxin | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0464CL | Mouse Anti-TFRC Recombinant Antibody (TAB-0464CL) | FuncS | Mouse IgG |
| TAB-0465CL | Mouse Anti-TFRC Recombinant Antibody (TAB-0465CL) | FuncS | Mouse IgG |
| TAB-616CT | Anti-Human TfR Recombinant Antibody (55-31) | ELISA, WB, IP | |
| TAB-617CT | Anti-Human TfR Recombinant Antibody (122-72) | ELISA, WB, IP | |
| TAB-618CT | Anti-Human TfR Recombinant Antibody (5D7-54.17) | ELISA, WB, IP |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-611CT | Humanized Anti-TFRC Recombinant Antibody (TAB-611CT) | ELISA | Humanized IgG |
| TAB-611CT-S(P) | Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-611CT-S(P)) | ELISA | Humanized scFv |
| TAB-612CT-S(P) | Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-612CT-S(P)) | ELISA | Humanized scFv |
| TAB-613CT-S(P) | Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-613CT-S(P)) | ELISA | Humanized scFv |
| TAB-614CT-S(P) | Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-614CT-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-615CT | Anti-Human TfR Recombinant Antibody (6-90) | ELISA, WB, IP |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-619CT-F(E) | Human Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-619CT-F(E)) | ELISA, WB | Human Fab |
| TAB-620CT-F(E) | Human Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-620CT-F(E)) | ELISA, WB | Human Fab |
| TAB-621CT-F(E) | Anti-Human TfR Recombinant Antibody Fab Fragment (LUCA31) | ELISA, WB, FC | Human antibody |
| TAB-623CT-F(E) | Anti-Human TfR Recombinant Antibody Fab Fragment (3TF12) | WB | Human antibody |
| TAB-624CT-F(E) | Anti-Human TfR Recombinant Antibody Fab Fragment (3TF2) | WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1999CQ | Rat Anti-Tfrc Recombinant Antibody (clone RI7217) | FC, ICC, IP, WB, Block | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3548 | Rabbit Anti-TFRC Recombinant Antibody (clone DS3548AB) | FC, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3370 | PE-DRB1*13:02/Human TFRC (NPGGYVAYSKAATVTGKL) MHC Tetramer | FCM | |
| MHC-LC3371 | PE-DRB1*13:02/Human TFRC (NPGGYVAYSKAATVTG) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0376-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0376-CN) | ELISA, FC | Mouse IgG |
| HPAB-0377-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0377-CN) | ELISA, FC | Mouse IgG |
| HPAB-0378-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0378-CN) | ELISA, FC | Mouse IgG |
| HPAB-0379-CN | Human Anti-TFRC Recombinant Antibody (HPAB-0379-CN) | ELISA, FC | Humanized IgG |
| HPAB-0380-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0380-CN) | ELISA, FC, IF, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-035LC-S(P) | Rat Anti-TFRC Recombinant Antibody (clone 9E4); scFv Fragment | FuncS, IHC, FC | Rat scFv |
| HPAB-2700LY-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-2700LY-S(P)) | ELISA | Mouse scFv |
| HPAB-2701LY-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-2701LY-S(P)) | ELISA | Mouse scFv |
| HPAB-2702LY-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-2702LY-S(P)) | ELISA | Mouse scFv |
| HPAB-AP469-YC-S(P) | Human Anti-TFRC Recombinant Antibody (clone c5D7); scFv Fragment | FC, WB, Cyt, Inhib, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0238-YJ-F(E) | Rat Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0238-YJ-F(E)) | IHC, FC, WB, FuncS | Rat Fab |
| HPAB-0239-YJ-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0239-YJ-F(E)) | IHC, FC, WB, FuncS | Mouse Fab |
| HPAB-0240-YJ-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0240-YJ-F(E)) | IHC, FC, WB, FuncS | Mouse Fab |
| HPAB-2692LY-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-2692LY-F(E)) | ELISA | Mouse Fab |
| HPAB-2693LY-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-2693LY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1481 | AbPlus™ Anti-TFRC Magnetic Beads (VS-0724-YC1481) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY205 | CytoStream™ Mouse Anti-TFRC Recombinant Antibody (clone OX-26) | FC, IHC, IP | Mouse IgG2a, kappa |
| VS-0225-XY206 | CytoStream™ Rat Anti-TFRC Recombinant Antibody (clone RI7217) | FC | Rat IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7200 | Anti-Mouse TFRC Immunohistochemistry Kit | IHC | |
| VS-0525-XY7201 | Anti-Rat TFRC Immunohistochemistry Kit | IHC |
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