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  • Recombinant Human Anti-TMEFF2 Antibody (clone 6G6)

Recombinant Human Anti-TMEFF2 Antibody (clone 6G6) (CAT#: VS4-CJ136)

This human anti-TMEFF2 antibody (clone 6G6) is a product that recognizes human TMEFF2. The immunogen of this antibody is recombinant human TMEFF2 protein. The mAb has been tested for use in ELISA.


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Normal Tissue
Figure 1 Cerebral cortex
Figure 1 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15587/35964_B_7_5.jpg
Figure 2 Colon
Figure 2 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15587/35964_A_9_3.jpg
Figure 3 Liver
Figure 3 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15587/35964_A_9_4.jpg
Figure 4 Kidney
Figure 4 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15587/35964_A_7_5.jpg
Figure 5 Testis
Figure 5 Testis
(Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15587/35964_A_5_6.jpg
Figure 6 Prostate
Figure 6 Prostate
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15587/35964_A_2_5.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15587/35964_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (AF22, LHCN-M2)
Figure 8 RNA cell line category: Group enriched (AF22, LHCN-M2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000144339-TMEFF2

Specifications

  • Immunogen
  • Recombinant Human TMEFF2 protein
  • Host Species
  • Human
  • Type
  • Human IgG4 (S228P)
  • Specificity
  • Human TMEFF2
  • Species Reactivity
  • Human
  • Clone
  • 6G6
  • Applications
  • ELISA
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Affinity chromatography
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Buffer
  • 50% Glycerol, 0.01M PBS, pH 7.4.
  • Preservative
  • 0.03% Proclin 300
  • Storage
  • Store at -20°C or -80°C upon receipt. Avoid repeated freeze.

Applications

  • Application Notes
  • This antibody has been tested for use in ELISA.

Target

  • Alternative Names
  • TR; HPP1; TPEF; TR-2; TENB2; CT120.2
  • Long Name
  • Transmembrane protein with EGF like and two follistatin like domains 2
  • Sequence Similarities
  • Belongs to the tomoregulin family.
  • Cellular Localization
  • Membrane, Secreted
  • Post Translation Modifications
  • O-glycosylated; contains chondroitin sulfate glycosaminoglycans.
    A soluble form (TMEFF2-ECD) is produced by proteolytic shedding. This shedding can be induced by phorbol ester or pro-inflammatory cytokines such as TNFalpha, and is mediated by ADAM17.
  • Function
  • May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.

Recommended Products

Isotype Control

Secondary Antibody

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "TMEFF2"

Recombinant Antibody

CAT Product Name Application Type
MOB-3543z Mouse Anti-TMEFF2 Recombinant Antibody (MOB-3543z) ELISA, IHC, WB, IF Mouse IgG
HPAB-0022-LS Mouse Anti-TMEFF2 Recombinant Antibody (clone TMEFF2#19) ELISA Humanized lgG

Fab Fragment Antibody

CAT Product Name Application Type
MOB-3543z-F(E) Recombinant Anti-Human TMEFF2 Antibody Fab Fragment IF, FuncS Fab
HPAB-0022-LS-F(E) Mouse Anti-TMEFF2 Recombinant Antibody (clone TMEFF2#19); Fab Fragment ELISA Humanized Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-3543z-S(P) Recombinant Anti-Human TMEFF2 Antibody scFv Fragment ELISA, WB, FuncS scFv
HPAB-0022-LS-S(P) Mouse Anti-TMEFF2 Recombinant Antibody (clone TMEFF2#19); scFv Fragment ELISA Humanized scFv

Mouse Antibody

CAT Product Name Application Type
TAB-0284CL Anti-Human TMEFF2 Recombinant Antibody (PQ01 (#001)) ELISA, WB, FuncS
TAB-0284CL-S(P) Anti-Human TMEFF2 Recombinant Antibody scFv Fragment (PQ01 (#001)) ELISA, WB, FuncS
TAB-0284CL-F(E) Anti-Human TMEFF2 Recombinant Antibody Fab Fragment (PQ01 (#001)) ELISA, WB, FuncS

Humanized Antibody

CAT Product Name Application Type
TAB-594CT Humanized Anti-TMEFF2 Recombinant Antibody (TAB-594CT) ELISA, FC, IHC Humanized antibody
TAB-594CT-S(P) Humanized Anti-TMEFF2 Recombinant Antibody; scFv Fragment (TAB-594CT-S(P)) ELISA, FC, IHC Humanized scFv
TAB-594CT-F(E) Humanized Anti-TMEFF2 Recombinant Antibody; Fab Fragment (TAB-594CT-F(E)) ELISA, FC, IHC Humanized Fab

Human Antibody

CAT Product Name Application Type
TAB-158CQ Anti-Human TMEFF2 Recombinant Antibody (AT-19) ELISA, FC, IF Human antibody
TAB-158CQ-S(P) Anti-Human TMEFF2 Recombinant Antibody scFv Fragment (AT-19) ELISA, FC, IF Human antibody
TAB-158CQ-F(E) Anti-Human TMEFF2 Recombinant Antibody Fab Fragment (AT-19) ELISA, FC, IF Human antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3590 Rabbit Anti-TMEFF2 Recombinant Antibody (clone DS3590AB) WB Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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