Recombinant Anti-TREM1 Vesicular Antibody, EV Displayed (VS-0425-YC229) (CAT#: VS-0425-YC229)

• Application
• Block, ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• TREM1

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Cynomolgus

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Triggering receptor expressed on myeloid cells 1

• Biological Process
• Adaptive immunity, Immunity, Innate immunity

• Molecular Function
• Receptor

• Cellular Localization
• Golgi apparatus

• Introduction
• This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

• Alternative Names
• CD354, TREM-1

• Gene ID
• 54210

• UniProt ID
• Q9NP99

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