Recombinant Anti-TSPAN8 Vesicular Antibody, EV Displayed (VS-0425-YC209)
CAT#: VS-0425-YC209
The Recombinant Anti-TSPAN8 Vesicular Antibody, EV Displayed (VS-0425-YC209) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TSPAN8-expressed cells or tissues. The TSPAN8 is a tetraspanin family member, mediating signal transduction events influencing cell development. It is expressed in carcinomas and utilizes alternate polyadenylation sites.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line OE19
Immunofluorescent staining of human cell line OE19 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/22273/1971_C4_6_selected.jpg
Normal Tissue
Figure 2 Colon
Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Microvilli Staining: High Intensity: Strong Goblet cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/44337/125265_A_9_3.jpg
Normal Tissue
Figure 3 Gallbladder
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/44337/125265_A_5_4.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (OE19)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000127324-TSPAN8
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TSPAN8
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Tetraspanin 8
- Cellular Localization
- Vesicles
- Introduction
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.
- Alternative Names
- CO-029, TM4SF3
- Gene ID
- 7103
- UniProt ID
- P19075
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Datasheet
MSDS
COA
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See other products for "TSPAN8"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-212CQ | Mouse Anti-TSPAN8 Recombinant Antibody (TAB-212CQ) | ELISA, IF, WB | Mouse IgG |
| TAB-212CQ-S(P) | Mouse Anti-TSPAN8 Recombinant Antibody; scFv Fragment (TAB-212CQ-S(P)) | ELISA, IF, WB | Mouse scFv |
| TAB-212CQ-F(E) | Mouse Anti-TSPAN8 Recombinant Antibody; Fab Fragment (TAB-212CQ-F(E)) | ELISA, IF, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-213CQ | Anti-Human TSPAN8 Recombinant Antibody (mAb4) | ELISA, FC, ICC, IHC | Human antibody |
| TAB-213CQ-S(P) | Anti-Human TSPAN8 Recombinant Antibody scFv Fragment (mAb4) | ELISA, FC, ICC, IHC | Human antibody |
| TAB-213CQ-F(E) | Anti-Human TSPAN8 Recombinant Antibody Fab Fragment (mAb4) | ELISA, FC, ICC, IHC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2064CT | Recombinant Mouse anti-Human TSPAN8 Monoclonal antibody (EML2293) | WB | |
| HPAB-0750-FY | Human Anti-TSPAN8 Recombinant Antibody (HPAB-0750-FY) | WB, Inhib | Chimeric (mouse/human) IgG |
| VS7-0425-WR1061 | Mouse Anti-TSPAN8 Recombinant Antibody (clone 8A4A10) | WB, IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0602MZ | Chicken Anti-TSPAN8 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0750-FY-F(E) | Mouse Anti-TSPAN8 Recombinant Antibody; Fab Fragment (HPAB-0750-FY-F(E)) | WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0750-FY-S(P) | Mouse Anti-TSPAN8 Recombinant Antibody; scFv Fragment (HPAB-0750-FY-S(P)) | WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC100 | Rabbit Anti-TSPAN8 Antibody (VS-0924-YC100) - Cancer Stem Cell Marker | IHC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY229 | CytoStream™ Rat Anti-TSPAN8 Recombinant Antibody (clone 458811) | FC | Rat IgG2b, kappa |
| VS-0225-XY230 | CytoStream™ Rat Anti-TSPAN8 Recombinant Antibody (clone 657909) | FC | Rat IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY137 | Human Anti-TSPAN8 scFv-Fc Chimera (VS-0325-FY137) | Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7580 | Anti-Mouse TSPAN8 Immunohistochemistry Kit | IHC |
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