Recombinant Mouse Anti-TTR Antibody (VS4-CJ145) (CAT#: VS4-CJ145)
This mouse anti-TTR antibody is a product that recognizes human TTR. The immunogen of this antibody is a recombinant protein corresponding to TTR. The mAb has been tested for use in ELISA, Western Blot (1:500-1:5000), Immunohistochemistry (1:50-1:500).
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2550/1030_B12_3_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2550/1030_B12_3_selected.jpg
Figure 2 IHC staining of human hippocampus
(Immunohistochemical staining of human hippocampus shows plasma positivity in blood vessels.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/ih_additional_tissue/2550/1625_959_400x400.jpg
(Immunohistochemical staining of human hippocampus shows plasma positivity in blood vessels.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/ih_additional_tissue/2550/1625_959_400x400.jpg
Figure 3 IHC staining of human liver
(Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2517/ihc_selected.jpg
(Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2517/ihc_selected.jpg
Figure 4 IHC staining of human pancreas
(Immunohistochemical staining of human pancreas shows selective positivity in islets of Langerhans.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62567/ihc_selected.jpg
(Immunohistochemical staining of human pancreas shows selective positivity in islets of Langerhans.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62567/ihc_selected.jpg
Figure 5 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows strong granular cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73406/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows strong granular cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73406/ihc_selected.jpg
Figure 6 Liver
(Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2517/6846_A_9_4.jpg
(Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2517/6846_A_9_4.jpg
Figure 7 Pancreas
(Pancreatic endocrine cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2550/141382_A_3_3.jpg
(Pancreatic endocrine cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2550/141382_A_3_3.jpg
Figure 8 Kidney
(Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73406/153523_A_7_5.jpg
(Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73406/153523_A_7_5.jpg
Figure 9 RNA cell line category: Cell line enhanced (CACO-2, EFO-21, Hep G2, U-2 OS)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118271-TTR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118271-TTR
Specifications
- Immunogen
- Recombinant Protein
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human TTR
- Species Reactivity
- Human
- Applications
- ELISA, WB, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Immunogen affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, PBS, pH 7.4.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Western Blot (1:500-1:5000), Immunohistochemistry (1:50-1:500).
Target
- Alternative Names
- ATTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTN
- Gene ID
- 7276
- UniProt ID
- P02766
- Long Name
- Transthyretin
- Sequence Similarities
- Belongs to the transthyretin family.
- Cellular Localization
- Amyloid, Cytoplasm, Secreted
- Post Translation Modifications
- Not glycosylated under normal conditions. Following unfolding, caused for example by variant AMYL-TTR 'Gly-38', the cryptic Asn-118 site is exposed and glycosylated by STT3B-containing OST complex, leading to its degradation by the ER-associated degradation (ERAD) pathway.
- Protein Refseq
- NP_000362.1
- Function
- Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TTR"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2498-sdAb | Recombinant Anti-human TTR VHH Single Domain Antibody | ELISA, Neut, ICC, FC | Llama VHH |
| HPAB-0483-YJ-VHH | Recombinant Camel Anti-TTR Single Domain Antibody (HPAB-0483-YJ-VHH) | ELISA | Camel VHH |
| HPAB-0484-YJ-VHH | Recombinant Camel Anti-TTR Single Domain Antibody (HPAB-0484-YJ-VHH) | ELISA | Camel VHH |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-128 | Mouse Anti-TTR Recombinant Antibody (clone 39-44); scFv Fragment | WB, Block | Mouse scFv |
| HPAB-0108-YC-S(P) | Human Anti-TTR Recombinant Antibody; scFv Fragment (HPAB-0108-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-0109-YC-S(P) | Human Anti-TTR Recombinant Antibody; scFv Fragment (HPAB-0109-YC-S(P)) | ELISA, WB, IP | Human scFv |
| HPAB-0110-YC-S(P) | Human Anti-TTR Recombinant Antibody; scFv Fragment (HPAB-0110-YC-S(P)) | ELISA, WB, IP | Human scFv |
| HPAB-0111-YC-S(P) | Human Anti-TTR Recombinant Antibody; scFv Fragment (HPAB-0111-YC-S(P)) | ELISA, WB, IP | Human scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0423CL | Human Anti-TTR Recombinant Antibody (TAB-0423CL) | ELISA, DB, WB, IF | Human IgG |
| TAB-0423CL-S(P) | Human Anti-TTR Recombinant Antibody; scFv Fragment (TAB-0423CL-S(P)) | ELISA, DB, WB, IF | Human scFv |
| TAB-0423CL-F(E) | Human Anti-TTR Recombinant Antibody; Fab Fragment (TAB-0423CL-F(E)) | ELISA, DB, WB, IF | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-165CQ | Mouse Anti-TTR Recombinant Antibody (TAB-165CQ) | ELISA, WB | Mouse IgG1, κ |
| TAB-166CQ | Mouse Anti-TTR Recombinant Antibody (TAB-166CQ) | ELISA, WB | Mouse IgG1, κ |
| TAB-165CQ-S(P) | Mouse Anti-TTR Recombinant Antibody; scFv Fragment (TAB-165CQ-S(P)) | ELISA, WB | Mouse scFv |
| TAB-166CQ-S(P) | Mouse Anti-TTR Recombinant Antibody; scFv Fragment (TAB-166CQ-S(P)) | ELISA, WB | Mouse scFv |
| TAB-165CQ-F(E) | Mouse Anti-TTR Recombinant Antibody; Fab Fragment (TAB-165CQ-F(E)) | ELISA, WB | Mouse Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1684CT | Recombinant Mouse anti-Human TTR Monoclonal antibody (20F2) | IP, WB | |
| HPAB-0108-YC | Human Anti-TTR Recombinant Antibody (HPAB-0108-YC) | ELISA, FuncS | Human IgG |
| HPAB-0109-YC | Human Anti-TTR Recombinant Antibody (HPAB-0109-YC) | ELISA, WB, IP | Human IgG |
| HPAB-0110-YC | Human Anti-TTR Recombinant Antibody (HPAB-0110-YC) | ELISA, WB, IP | Human IgG |
| HPAB-0111-YC | Human Anti-TTR Recombinant Antibody (HPAB-0111-YC) | ELISA, WB, IP | Human IgG |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0600MZ | Chicken Anti-Transthyretin Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3717 | Rabbit Anti-TTR Recombinant Antibody (clone DS3717AB) | FC, ICC, IHC-P, IP, WB | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0694-CN-F(E) | Mouse Anti-TTR Recombinant Antibody (clone AD7F6); Fab Fragment | WB, ELISA, IHC, IP | Mouse Fab |
| HPAB-0642LY-F(E) | Mouse Anti-TTR Recombinant Antibody (clone 14G8); Fab Fragment | WB, FC, ELISA | Mouse Fab |
| HPAB-0643LY-F(E) | Human Anti-TTR Recombinant Antibody (clone Hu14G8v1); Fab Fragment | WB, FC, ELISA | Humanized Fab |
| HPAB-0644LY-F(E) | Human Anti-TTR Recombinant Antibody (clone Hu14G8v2); Fab Fragment | WB, FC, ELISA | Humanized Fab |
| HPAB-0645LY-F(E) | Human Anti-TTR Recombinant Antibody (clone Hu14G8v3); Fab Fragment | WB, FC, ELISA | Humanized Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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