Recombinant Anti-TYRP1 Vesicular Antibody, EV Displayed (VS-0425-YC256)
CAT#: VS-0425-YC256
The Recombinant Anti-TYRP1 Vesicular Antibody, EV Displayed (VS-0425-YC256) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TYRP1-expressed cells or tissues. The TYRP1 is a tyrosinase family enzyme involved in melanin biosynthesis, associated with forms of albinism.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/937/1291_B1_3_selected.jpg
Normal Tissue
Figure 2 Skin
Melanocytes
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/937/1995_B_9_1.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000107165-TYRP1/subcellular
❮
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TYRP1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Tyrosinase related protein 1
- Biological Process
- Melanin biosynthesis
- Molecular Function
- Monooxygenase, Oxidoreductase
- Cellular Localization
- Vesicles
- Introduction
- This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.
- Alternative Names
- b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP
- Gene ID
- 7306
- UniProt ID
- P17643
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Datasheet
MSDS
COA
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|---|---|---|---|
| MOB-1020-F(E) | Recombinant Anti-human TYRP1 Antibody Fab Fragment | ELISA, FuncS | Fab |
| MHH-1020-F(E) | Recombinant Human Anti-human TYRP1 Antibody Fab Fragment | IF, FACS, FuncS | Fab |
| HPAB-0121-LSX-F(E) | Human Anti-TYRP1 Recombinant Antibody (clone 20D7); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0122-LSX-F(E) | Human Anti-TYRP1 Recombinant Antibody (clone 20D7S); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0123-LSX-F(E) | Human Anti-TYRP1 Recombinant Antibody (clone CTA99); Fab Fragment | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1020-S(P) | Recombinant Anti-human TYRP1 Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| MHH-1020-S(P) | Recombinant Human Anti-human TYRP1 Antibody scFv Fragment | WB, IHC, FuncS | scFv |
| HPAB-0121-LSX-S(P) | Human Anti-TYRP1 Recombinant Antibody (clone 20D7); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0122-LSX-S(P) | Human Anti-TYRP1 Recombinant Antibody (clone 20D7S); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0123-LSX-S(P) | Mouse Anti-TYRP1 Recombinant Antibody (clone CTA99); scFv Fragment | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-130 | Anti-Human TYRP1 Recombinant Antibody (Flanvotumab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-1020 | Recombinant Human Anti-human TYRP1 Antibody | ELISA, IF, FuncS | IgG |
| HPAB-0121-LSX | Human Anti-TYRP1 Recombinant Antibody (clone 20D7) | ELISA, FC | Human IgG1, κ |
| HPAB-0122-LSX | Human Anti-TYRP1 Recombinant Antibody (clone 20D7S) | ELISA, FC | Human IgG1, κ |
| MRO-1533-CN | Rabbit Anti-TYRP1 Recombinant Antibody (clone JU36-48) | WB, IF, IHC, IP | Rabbit IgG |
| VS13-YC1196 | Rabbit Anti-TYRP1 Recombinant Antibody (VS13-YC1196) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3737 | Rabbit Anti-TYRP1 Recombinant Antibody (clone DS3737AB) | WB, IHC-P, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY192 | Human Anti-TYRP1 (clone Flanvotumab) scFv-Fc Chimera | FC, ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7671 | Anti-TYRP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7672 | Anti-Mouse TYRP1 Immunohistochemistry Kit | IHC |
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