Recombinant Rabbit Anti-USP14 Antibody (clone 28C4) (CAT#: VS4-CJ150)
This rabbit anti-USP14 antibody (clone 28C4) is a product that recognizes human USP14. The immunogen of this antibody is a synthesized peptide derived from human USP14. The mAb has been tested for use in ELISA, Western Blot (1:500-1:2000), Immunofluorescence (1:50-1:200).
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1308/59_C4_2_selected.jpg

(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1308/3920_B_8_5.jpg

(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1308/3920_A_9_3.jpg

(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1308/3920_A_8_4.jpg

(Exocrine glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1308/3920_A_2_3.jpg

(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1308/3920_A_9_5.jpg

(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1308/3920_A_5_6.jpg

(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1308/3920_A_8_8.jpg

(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101557-USP14
Specifications
- Immunogen
- A synthesized peptide derived from human USP14
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human USP14
- Species Reactivity
- Human
- Clone
- 28C4
- Applications
- ELISA, WB, IF
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 150 mM NaCl, PBS, pH 7.4.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Western Blot (1:500-1:2000), Immunofluorescence (1:50-1:200).
Target
- Alternative Names
- TGT; Ubp6
- Gene ID
- 9097
- UniProt ID
- P54578
- Long Name
- Ubiquitin specific peptidase 14
- Sequence Similarities
- Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
- Cellular Localization
- Cell membrane, Cytoplasm, Membrane, Proteasome
- Protein Refseq
- NP_001032411.1; NP_005142.1
- Function
- Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome (PubMed:18162577, PubMed:28396413).
Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell (PubMed:18162577).
Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (PubMed:19106094).
Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1 (PubMed:19135427).
Indispensable for synaptic development and function at neuromuscular junctions (NMJs) (By similarity).
Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation (PubMed:27666593).
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "USP14"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2173CT | Recombinant Mouse anti-Human USP14 Monoclonal antibody (EML864) | WB | |
MRO-1562-CN | Rabbit Anti-USP14 Recombinant Antibody (clone JU30-49) | WB, IF, IHC, FC | Rabbit IgG |
VS3-QX1222 | Mouse Anti-USP14 Recombinant Antibody (clone 889CT6.2.1) | WB, FC | Mouse IgG1 |
VS3-CJ1037 | Mouse Anti-USP14 Recombinant Antibody (VS3-CJ1037) | WB, FC | Mouse IgG1 |
VS3-XY3536 | Rabbit Anti-USP14 Recombinant Antibody (clone R09-8E9) | WB, ICC, IF, FC | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS4-CJ150. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, WB, Neut, Funcs, IHC, Inhib
Application: Neut
Application: ELISA, WB
Application: ELISA, FC
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.