Recombinant Anti-VCAM1 Vesicular Antibody, EV Displayed (VS-0425-YC605) (CAT#: VS-0425-YC605)

The Recombinant Anti-VCAM1 Vesicular Antibody, EV Displayed (VS-0425-YC605) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to VCAM1-expressed cells or tissues. VCAM1 is a sialoglycoprotein mediating leukocyte-endothelial adhesion, with roles in atherosclerosis and rheumatoid arthritis. It is a member of the immunoglobulin superfamily.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Recombinant Antibody

  • Application
  • ELISA, FC, Neut, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • VCAM1
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human, Mouse
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Vascular cell adhesion molecule 1
  • Biological Process
  • Cell adhesion
  • Cellular Localization
  • Cell Junctions
  • Introduction
  • This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
  • Alternative Names
  • CD106

Related Resources

  • Related Signaling Pathways
  • Related Diseases

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "VCAM1"

Select a product category from the dropdown menu below to view related products.
Please select product type
Single Domain Antibodies Intrabodies Human Antibodies Humanized Antibodies Blocking Antibodies Neutralizing Antibodies Rabbit Monoclonal Antibodies ScFv Antibodies Neuroscience Antibodies IgG Antibodies Fab Antibodies Antibody Magnetic Beads FC Reagents & Kits ScFv-Fc Chimeras IHC Kits & Antibodies
CAT Product Name Application Type
NABL-061 Recombinant Anti-Human VCAM1 VHH Single Domain Antibody WB, ELISA, IP, FuncS Llama VHH

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for VS-0425-YC605. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Go to compare

Go to compare