Recombinant Anti-VSIR Vesicular Antibody, EV Displayed (VS-0425-YC697)
CAT#: VS-0425-YC697
The Recombinant Anti-VSIR Vesicular Antibody, EV Displayed (VS-0425-YC697) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to VSIR-expressed cells or tissues. VSIR enables activities like enzyme binding and acts within processes like T cell proliferation regulation, expressed in the immune system and other organs.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7968/if_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (CAPAN-2, HaCaT, HMC-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107738-VSIR
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Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- VSIR
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- V-set immunoregulatory receptor
- Molecular Function
- Receptor
- Introduction
- Predicted to enable endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Acts upstream of or within several processes, including negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of T cell cytokine production; and positive regulation of BMP signaling pathway. Located in external side of plasma membrane. Is expressed in several structures, including immune system; liver; lung; male reproductive gland or organ; and small intestine lamina propria. Orthologous to human VSIR (V-set immunoregulatory receptor).
- Alternative Names
- 4632428N05Rik, Dies1, PD-1H, VISTA
- Gene ID
- 74048
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "Vsir"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2274CQ | Hamster Anti-Vsir Recombinant Antibody (clone MH5A) | FC, Block, IHC, WB | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-036LC | Hamster Anti-VSIR Recombinant Antibody (clone YC160) | FuncS, WB | Hamster IgG |
| FAMAB-1490CQ | Mouse Anti-VSIR Recombinant Antibody (clone mam82) | Block, ELISA, IHC | Mouse IgG1 |
| VS13-YC1221 | Rabbit Anti-VSIR Recombinant Antibody (VS13-YC1221) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7875 | Anti-VSIR Immunohistochemistry Kit | IHC | |
| VS-0525-XY7876 | Anti-Mouse VSIR Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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