Recombinant Anti-VSIR Vesicular Antibody, EV Displayed (VS-0425-YC697) (CAT#: VS-0425-YC697)

• Application
• Block, ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• VSIR

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Mouse

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• V-set immunoregulatory receptor

• Molecular Function
• Receptor

• Introduction
• Predicted to enable endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Acts upstream of or within several processes, including negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of T cell cytokine production; and positive regulation of BMP signaling pathway. Located in external side of plasma membrane. Is expressed in several structures, including immune system; liver; lung; male reproductive gland or organ; and small intestine lamina propria. Orthologous to human VSIR (V-set immunoregulatory receptor).

• Alternative Names
• 4632428N05Rik, Dies1, PD-1H, VISTA

• Gene ID
• 74048

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