Recombinant Mouse Anti-WT1 Antibody (clone 9D1-8B8-4B8) (CAT#: VS3-FY1557)
This product is a recombinant mouse antibody that recognizes WT1. This antibody has been reported for use in Immunohistochemistry-Paraffin. The clone 9D1-8B8-4B8 is specific for human WT1. The antigen is synthetic peptide 1 (wt1) derived from human wilms tumor.
Specific Inquiry
IHC-P
Figure 1. Recombinant Mouse Anti-WT1 Antibody (clone 9D1-8B8-4B8) in IHC-P.
Immunohistochemical analysis of paraffin-embedded mesothelioma using Wilms tumor protein antibody. High pressure and high temperature sodium citrate pH 6.0 for antigen retrieval.
IHC-P
Figure 2. Recombinant Mouse Anti-WT1 Antibody (clone 9D1-8B8-4B8) in IHC-P.
Immunohistochemical analysis of paraffin-embedded mesothelioma using Wilms tumor protein antibody. High pressure and high temperature sodium citrate pH 6.0 for antigen retrieval.
Specifications
- Immunogen
- Synthetic peptide 1 (WT1) derived from human Wilms tumor.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human WT1
- Species Reactivity
- Human
- Clone
- 9D1-8B8-4B8
- Applications
- Immunohistochemistry-Paraffin
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS, pH 7.3, 50% glycerol, 0.5% BSA
- Preservative
- 0.02% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry-Paraffin: 1/100-1/500
Target
- Alternative Names
- Wilms Tumor 1; WT33; Wilms Tumor Protein; NPHS4; WIT-2; WAGR; AWT1; GUD
- Gene ID
- 7490
- UniProt ID
- P19544
- Sequence Similarities
- Belongs to the EGR C2H2-type zinc-finger protein family.
- Cellular Localization
- Cytoplasm, Nucleus
- Protein Refseq
- NP_000369.3; NP_001185480.1; NP_001185481.1
- Function
- Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533).
Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363).
Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190).
Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801).
Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921).
Recommended Products
Secondary Antibody
Isotype Control
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1458z | Mouse Anti-WT1 Recombinant Antibody (clone 24C8) | FC, IF, IHC | Mouse IgG1, κ |
| ZG-0176C | Mouse Anti-WT1 Recombinant Antibody (clone ABT-WT1) | IHC-P, IF | Mouse IgG |
| ZG-0177C | Mouse Anti-WT1 Recombinant Antibody (clone PT0264) | IHC-P, IF | Mouse IgG |
| VS3-XY1601 | Mouse Anti-WT1 Recombinant Antibody (clone 7B11D6) | ELISA, WB, FC | Mouse IgG1 |
| VS3-FY1556 | Recombinant Mouse Anti-WT1 Antibody (clone 7F9E8) | ELISA, WB, IHC, FC | Mouse IgG1 |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G065R | Anti-WT1 immunotoxin 6F-H2 (IgG)-RTA | Cytotoxicity assay, Function study |
MHC Tetramer for Cancer
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3886 | Rabbit Anti-WT1 Recombinant Antibody (clone DS3886AB) | WB, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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