Recombinant Anti-XCR1 Vesicular Antibody, EV Displayed (VS-0425-YC168)
CAT#: VS-0425-YC168
The Recombinant Anti-XCR1 Vesicular Antibody, EV Displayed (VS-0425-YC168) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to XCR1-expressed cells or tissues. The XCR1 is a chemokine receptor from the G protein-coupled receptor superfamily, involved in signal transduction by increasing intracellular calcium ions.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13169/38335_B_7_5.jpg
Normal Tissue
Figure 2 Lung
Macrophages
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13169/38335_A_3_4.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13169/38335_A_9_3.jpg
Normal Tissue
Figure 4 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13169/38335_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HEL, Karpas-707, RT4, U-266/84, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000173578-XCR1
❮
❯
Recombinant Antibody
- Application
- Cyt, ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- XCR1
- Host Animal
- Human
- Antibody Isotype
- IgG2 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- X-C motif chemokine receptor 1
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Introduction
- The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
- Alternative Names
- CCXCR1, GPR5
- Gene ID
- 2829
- UniProt ID
- P46094
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Datasheet
MSDS
COA
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See other products for "Xcr1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-376CQ | Anti-Human XCR1 Recombinant Antibody (TAB-376CQ) | Cyt, FC, FuncS, Neut | Chimeric antibody (mouse/human) |
| TAB-376CQ-S(P) | Anti-Human XCR1 Recombinant Antibody scFv Fragment (TAB-376CQ-S(P)) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-376CQ-F(E) | Anti-Human XCR1 Recombinant Antibody Fab Fragment (TAB-376CQ-F(E)) | ELISA, FC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-377CQ | Anti-Human XCR1 Recombinant Antibody (TAB-377CQ) | ELISA | Humanized antibody |
| TAB-377CQ-S(P) | Anti-Human XCR1 Recombinant Antibody scFv Fragment (TAB-377CQ-S(P)) | ELISA, FC | Humanized antibody |
| TAB-378CQ-S(P) | Anti-Human XCR1 Recombinant Antibody scFv Fragment (TAB-378CQ-S(P)) | ELISA, FC | Humanized antibody |
| TAB-377CQ-F(E) | Anti-Human XCR1 Recombinant Antibody Fab Fragment (TAB-377CQ-F(E)) | ELISA, FC | Humanized antibody |
| TAB-378CQ-F(E) | Anti-Human XCR1 Recombinant Antibody Fab Fragment (TAB-378CQ-F(E)) | ELISA, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-173YJL | Mouse Anti-Xcr1 Recombinant Antibody (clone MARX10) | ELISA, FC | Mouse IgG2b |
| VS11-QX144 | Mouse Anti-XCR1 Recombinant Antibody (clone 5G7) | ELISA, FC | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-173YJL-S(P) | Mouse Anti-Xcr1 Recombinant Antibody (clone MARX10); scFv Fragment | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-173YJL-F(E) | Mouse Anti-Xcr1 Recombinant Antibody (clone MARX10); Fab Fragment | ELISA, FC | Mouse Fab |
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