Creative Biolabs offers comprehensive research services and high-quality products across multiple critical areas of cellular and molecular biology. Our expertise spans fundamental cellular processes, cancer biology, and the development of therapeutic strategies. With state-of-the-art facilities, experienced scientists, and an extensive catalog of research-grade products, we provide cutting-edge solutions to advance your research projects from basic discovery to translational applications. Whether you need custom services, ready-to-use reagents, or specialized tools, we deliver the resources necessary to accelerate your scientific discoveries.

Cellular Processes and Mechanisms

Cell Cycle

Our cell cycle research services offer comprehensive analysis of the orchestrated sequence of events controlling cell division. We specialize in studying cell cycle checkpoints (G1/S, G2/M, and spindle assembly), regulatory mechanisms involving cyclins and CDKs, DNA repair pathways, and the critical p53 tumor suppressor pathway. These services are essential for understanding cell proliferation, genomic stability, and the development of cancer therapeutics targeting cell cycle dysfunction.

Cell Metabolism

Cell metabolism research at Creative Biolabs encompasses the complex networks of chemical reactions that sustain cellular life. Our services include detailed analysis of amino acid delivery systems, fatty acid synthesis pathways, glycolysis, mitochondrial metabolism, and lipid cholesterol homeostasis. We provide sophisticated metabolic profiling and flux analysis to understand how cells generate energy, synthesize biomolecules, and maintain metabolic balance in various physiological and pathological states.

Autophagy

Autophagy is a fundamental cellular process essential for maintaining cellular homeostasis through the degradation and recycling of cellular components. Our autophagy research services cover the comprehensive analysis of key regulatory pathways including AMPK activation, ATG protein function, mTOR complex signaling, and Rab protein-mediated vesicular transport. We provide advanced techniques to study autophagosome formation, maturation, and fusion with lysosomes, helping researchers understand this critical process in both physiological and pathological conditions.

Apoptosis

Our apoptosis research services focus on the intricate mechanisms of programmed cell death, a vital process for development and tissue homeostasis. We offer comprehensive analysis of both extrinsic and intrinsic apoptotic pathways, including death receptor-ligand interactions, caspase activation cascades, Bcl-2 family dynamics, and mitochondrial involvement. Our expertise covers various aspects from chromatin condensation to the role of transcription factors like p53, providing insights crucial for understanding disease mechanisms and developing therapeutic interventions.

Cancer Biology and Therapeutics

Signal Transduction in Cancer

We provide extensive research services in cancer signal transduction, focusing on the dysregulated pathways that drive tumor development and progression. Our expertise covers multiple signaling cascades including FAK-Src signaling, PI3K pathway, PKC family proteins, RAS-MAPK pathway, Rho GTPases, and the ubiquitin-proteasome system. These services help identify therapeutic targets and develop strategies to interrupt aberrant signaling in cancer cells.

Cancer Biomarkers

Our cancer biomarker services encompass the discovery, validation, and detection of molecular indicators for cancer diagnosis, prognosis, and treatment monitoring. We offer comprehensive analysis of various biomarker types including DNA/RNA markers, protein biomarkers, and tissue-specific indicators. Our advanced detection methods range from immunohistochemistry and liquid biopsy to mass spectrometry and next-generation sequencing, supporting precision medicine approaches in oncology.

Cancer Immunology

Creative Biolabs offers cutting-edge cancer immunology services exploring the complex interactions between the immune system and cancer. Our research areas include CAR-T cell therapy target identification, cytokine profiling in tumorigenesis, immune checkpoint analysis, and tumor antigen characterization. These services support the development of innovative immunotherapies that harness the body's natural defenses against cancer.

Oncoproteins

Our oncoprotein research services focus on proteins that drive malignant transformation through mutation or overexpression. We analyze how oncoproteins affect apoptosis regulation, cell cycle control, growth factor signaling, and transcriptional regulation. Our comprehensive approach includes studying growth factor receptors, signal transducers, and transcription factors that contribute to cancer development, providing crucial insights for targeted therapy development.

For research use only. Not intended for any clinical use.