Senescence Marker Antibody Panel (CDKN1A, CDKN2A, RB1, TP53)
CAT#: VS-0725-YC38
The Senescence Marker Antibody Panel are sets of 7 antibodies, enabling the simultaneous detection of key proteins associated with cellular senescence. Our extensive set includes antibodies against CDKN1A, CDKN2A, phosphorylated RB1 (pThr 252), phosphorylated RB1 (pSer 807), phosphorylated RB1 (pSer 811), and TP53. This panel offers a powerful and streamlined tool for understanding age-related pathologies and tumor suppression, consistently delivering robust and reproducible data.
| Sub Cat | Component Name | Clone | Type | Target | Species Reactivity | Applications | |
| HPAB-M0037-YC | Mouse Anti-CDKN2A Recombinant Antibody (clone P1) | P1 | Mouse IgG | CDKN2A | Human | ELISA | |
| HPAB-A1323-YJ | Human Anti-TP53 Recombinant Antibody (clone 163.5) | 163.5 | Human IgG1 | TP53 | Human | ELISA, IP | |
| VS3-XY3308 | Rabbit Anti-CDKN1A Recombinant Antibody (clone R04-4H1) | R04-4H1 | Rabbit IgG | CDKN1A | Human, Mouse, Rat | WB, ICC, IF | |
| VS3-QX960 | Mouse Anti-RB1 Recombinant Antibody (clone 7H10-C5-E6) | 7H10-C5-E6 | Mouse IgG1 | RB1 | Human | WB, IHC, ICC, FC, ELISA | |
| VS3-CJ436 | Rabbit Anti-RB1 (phospho S807) Recombinant Antibody (VS3-CJ436) | Rabbit IgG | RB1 | Human, Mouse, Rat | WB, ICC, IF, IHC | ||
| VS3-FY1252 | Recombinant Rabbit Anti-RB1 (phospho Ser811) Antibody (clone R01-2G6) | R01-2G6 | Rabbit IgG | RB1 | Human, Hamster | Western Blot | |
| VS3-FY1254 | Recombinant Rabbit Anti-RB1 (phospho Thr252) Antibody (clone R03-8H1) | R03-8H1 | Rabbit IgG | RB1 | Human, Rat | Western Blot, Immunohistochemistry-Paraffin |
More Infomation
Specifications
- Targets
- CDKN1A, CDKN2A, RB1 (pThr 252), RB1 (pSer 807), RB1 (pSer 811), TP53
- Species Reactivity
- Human
- Research Area
- Senescence Marker
- Introduction
- Cellular senescence is a stable state of irreversible cell cycle arrest that healthy cells enter in response to various stressors, including replicative exhaustion (telomere shortening), oncogene activation, DNA damage, and oxidative stress. Unlike quiescence, from which cells can re-enter the cell cycle, senescent cells remain metabolically active and often undergo profound phenotypic changes, collectively known as the Senescence-Associated Secretory Phenotype (SASP). While senescence serves as a potent tumor suppressive mechanism by preventing the proliferation of potentially damaged cells, the accumulation of senescent cells in tissues contributes significantly to aging and various age-related diseases.
- Storage
- Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0725-YC38. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: ELISA, WB, BLI, SPR
Application: ELISA, FC, IF, WB
-3.jpg)
Application: Neut
Application: Neut, ELISA, WB, SPR, IF, EM
Application: IF, ICC, WB, IHC-P, IP
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
