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α-GalCer (C24)
Loading...Anti-α-GalCer (C24) Products
- Mouse Anti-α-GalCer (C24) Recombinant Soluble TCR (clone Vβ8.2) (scTCR-1416YC-S(P))
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- Epitope: α-galactosylceramide (C24)
- MHC: mouse CD1d
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- Recombinant Mouse Anti-α-GalCer (C24) Soluble TCR (Vβ8.2) (C-Cys) (VS-0622-YF5413)
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- Epitope: α-galactosylceramide (C24)
- MHC: mouse CD1d
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- Recombinant Mouse Anti-α-GalCer (C24) Soluble TCR (Vβ8.2) (KIH) (VS-0622-YF8121)
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- Epitope: α-galactosylceramide (C24)
- MHC: mouse CD1d
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For Research Use Only. Not For Clinical Use.
Background
alpha-Galactosylceramide (α-GalCer, KRN7000) is a synthetic glycolipid derived from structure-activity relationship studies of galactosylceramides isolated from the marine sponge Agelas mauritianus. α-GalCer is a strong immunostimulant and shows potent anti-tumour activity in many in vivo models. α-GalCer is a potent activator of iNKT cells, and a model CD1d antigen. The invariant T cell receptor of the iNKT cell is able to bind the CD1d:glycolipid complex leading to iNKT cell in both mice and humans.