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ABLIM1
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Anti-ABLIM1 Products
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Astrocytes, Cardiomyocytes, Squamous epithelial cells, Peritubular cells)
Immune cell specificity
Immune cell enhanced (naive CD4 T-cell)
Cell line specificity
Cell line enhanced (hTCEpi, OE19)
Interaction
Binds F-actin. Interacts with ABRA.
Molecular function
Actin-binding
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