Anti-ACTN1 Products

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For Research Use Only. Not For Clinical Use.

Are you struggling with unreliable antibody performance in cell adhesion or motility studies? Our Anti-ACTN1 Recombinant Antibodies leverage Creative Biolabs' proprietary mammalian expression systems and rigorous epitope validation to deliver unmatched specificity for cytoskeletal research. Designed for consistency across applications like immunofluorescence and protein interaction assays, these antibodies streamline complex studies of cell structure, migration, and mechanotransduction.

ACTN1: A Structural Linchpin in Cellular Dynamics

Due to their specificity and the critical role of ACTN1 in cellular processes, anti-ACTN1 recombinant antibodies from Creative Biolabs are valuable tools in various research and diagnostic applications. An Anti-ACTN1 Recombinant Antibody is a precisely engineered tool that leverages the advantages of recombinant technology to reliably detect and study the crucial cytoskeletal protein ACTN1 in diverse biological contexts.

Alternative Names

Alpha-actinin-1; F-Actinin Cross-Linking Protein; Non-Muscle Alpha-Actinin-1; ACTN; Cytoskeletal Actin-Binding Protein 1.

Background

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Anti-ACTN1 rAb Products

Creative Biolabs' recombinant antibodies against ACTN1 combine high-affinity binding with batch-to-batch reproducibility. Optimized for applications ranging from super-resolution microscopy to flow cytometry, these tools empower precise interrogation of cytoskeletal dynamics in physiological and disease models.

Table.1 Featured anti-ACTN1 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs employs a stringent quality control protocol for its anti-ACTN1 recombinant antibodies, subjecting each batch to exhaustive validation to verify specificity, sensitivity, and functionality. This meticulous strategy ensures our antibodies align with the highest industry standards, delivering exceptional performance and dependability for even the most challenging applications.

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rAb Production

Our serum-free mammalian platform ensures glycosylation-matched ACTN1 antibodies at any scale—from µg to g/L yields. Integrated mass spectrometry and endotoxin testing guarantee compliance with in vivo therapeutic development standards.

Featured Anti-ACTN1 Recombinant Antibody Production Platforms
Fig.5 Milligram-scale synthesis of recombinant anti-ACTN1 antibodies.

Fig.6 Gram-scale fabrication of recombinant anti-ACTN1 antibodies.

rAb Modalities

Tailor your research with formats including Fab fragments, bispecifics, and fluorophore-conjugates. These modular designs support applications from live-cell imaging to cell targeting, adaptable to your experimental needs.

Fig.7 Modalities and production of full-length recombinant anti-ACTN1 antibodies.

With many years of expertise in cytoskeletal protein research, Creative Biolabs delivers rigorously validated tools to decode ACTN1's multifaceted roles. Contact our team today to discuss custom projects or request a product catalog.