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ADAM7

This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. [provided by RefSeq, Oct 2011]
Protein class

Disease related genes, Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enriched (Early spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (BEWO, NB-4, RPMI-8226, SH-SY5Y)

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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