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ADAM7
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- Mouse Anti-ADAM7 Recombinant Antibody (clone 4D1) (MRO-0685-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: WB, IF, IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. [provided by RefSeq, Oct 2011]
Protein class
Disease related genes, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enriched (Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (BEWO, NB-4, RPMI-8226, SH-SY5Y)
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