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ADCYAP1R1

This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
Protein class

G-protein coupled receptors, Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Astrocytes, Inhibitory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, NTERA-2, SCLC-21H, SH-SY5Y)

Interaction

Interacts (via N-terminal extracellular domain) with ADCYAP1.

Molecular function

Developmental protein, G-protein coupled receptor, Receptor, Transducer

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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