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AGER
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).
Protein class
Cancer-related genes, Plasma proteins, Transporters
Predicted location
Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enriched (Alveolar cells type 1)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HEK93, JURKAT, RPTEC TERT1, U-266/70, U-266/84)
Interaction
Interacts with S100A1 and APP (By similarity). Interacts with S100B, S100A12 and S100A14. Constitutive homodimer; disulfide-linked.
More Types Infomation
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- Derivation: Rabbit
- Species Reactivity: Mouse
- Type: Rabbit scFv
- Application: ELISA, Neut
- Recombinant Human Anti-human AGER Antibody scFv Fragment (MHH-44-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, Neut, FuncS
- Recombinant Human Anti-human AGER Antibody Fab Fragment (MHH-44-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, WB, Dot, FuncS
- Recombinant Anti-human AGER Antibody Fab Fragment (MOB-44-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, Nert, FuncS
-
- Derivation: Rabbit
- Species Reactivity: Mouse
- Type: Rabbit Fab
- Application: ELISA, Neut
- Recombinant Anti-human AGER Antibody scFv Fragment (MOB-44-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, IP, FuncS
- Rabbit Anti-AGER Recombinant Antibody (clone JF0975) (MRO-1317-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
-
- Derivation: Rabbit
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA, Neut
- Recombinant Anti-human AGER Antibody (MOB-44)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC, FuncS
- Mouse Anti-AGER Recombinant Antibody (clone EML133) (MOB-1390CT)
-
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: FC, IHC-P, WB
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IP, FuncS
- Mouse Anti-AGER Recombinant Antibody (clone 8D11) (NEUT-016CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG2
- Application: WB, Neut
- Mouse Anti-AGER Recombinant Antibody (clone CBL155) (NEUT-017CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG2
- Application: Neut, WB
-
- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, FC
- Mouse Anti-AGER Recombinant Antibody (clone CBL401) (NEUT-018CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: Block, WB, ELISA
- Rabbit Anti-AGER Antibody (clone H4), mRNA (PABZ-175-mRNA)
-
- Species Reactivity: Mouse
- Human Anti-AGER Recombinant Antibody; scFv Fragment (HPAB-N0016-YC-S(P)) (HPAB-N0016-YC-S(P))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Mouse Anti-AGER Recombinant Antibody (HPAB-1478-FY) (HPAB-1478-FY)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-AGER Recombinant Antibody (clone 2A11); Fab Fragment (HPAB-0341-FY-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab, κ
- Application: WB, IHC, ELISA, FC
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For Research Use Only. Not For Clinical Use.