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AHSA1
Loading...Anti-AHSA1 Products
- Anti-AHSA1 Immunohistochemistry Kit (VS-0525-XY235)
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- Species Reactivity: Human
- Target: AHSA1
- Application: IHC
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- Anti-Mouse AHSA1 Immunohistochemistry Kit (VS-0525-XY236)
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- Species Reactivity: Human, Mouse, Rat
- Target: AHSA1
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360).
Protein class
Plasma proteins, Transporters
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with HSPCA/HSP90 (PubMed:12504007, PubMed:12604615). Interacts (phosphorylated on Tyr-223) with HSP90AA1; the interaction activates HSP90AA1 ATPase activity (PubMed:27353360, PubMed:29127155). Interacts with HSP90AB1 (By similarity). Interacts with GCH1 (PubMed:16696853). Interacts with SRPK1 (PubMed:19240134). Interacts with FLCN (PubMed:27353360). (Microbial infection) Interacts with vesicular stomatitis virus glycoprotein (VSV G) (via cytoplasmic tail).
Molecular function
Chaperone
More Types Infomation