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ALOX15
Loading...Anti-ALOX15 Products
- Mouse Anti-NHP ALOX15 Recombinant Antibody (clone OTI3G8) (VS-1024-XY21)
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- Species Reactivity: Human, Non-human primate, Rat
- Type: Mouse IgG2b
- Application: WB, IHC, ICC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to regulate inflammation and immunity. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
Protein class
Disease related genes, Enzymes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Group enriched (Respiratory ciliated cells, Langerhans cells, Club cells)
Immune cell specificity
Immune cell enriched (eosinophil)
Cell line specificity
Group enriched (HMC-1, MCF7, T-47d)
Interaction
Interacts with PEBP1; in response to IL13/interleukin-13, prevents the interaction of PEBP1 with RAF1 to activate the ERK signaling cascade.
Molecular function
Dioxygenase, Oxidoreductase
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