ANO5

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a member of the anoctamin family of transmembrane proteins. The encoded protein is likely a calcium activated chloride channel. Mutations in this gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described.
Protein class

Disease related genes, Human disease related genes, Potential drug targets, Transporters

Predicted location

Membrane

Single cell type specificity

Group enriched (Excitatory neurons, Inhibitory neurons, Cardiomyocytes, Oligodendrocyte precursor cells, Astrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (A549, HAP1, HEK93, NTERA-2, RPTEC TERT1, U-266/84)

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