Anti-APOBR Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs has entered the cardiovascular space with the launch of highly specific anti-Apolipoprotein B Receptor (APOBR) recombinant antibodies for a novel lipoprotein receptor. While the LDL receptor is well-characterized and established in lipid metabolism research, APOBR has been identified as an alternative, yet related, pathway for lipoprotein clearance. Our top-quality antibodies are specifically designed for researchers who are characterizing this related receptor, exploring its role in lipid metabolism and atherosclerosis, and potentially identifying new therapeutic targets.

APOBR: An Alternative Receptor for Apolipoprotein B-Containing Lipoproteins

APOBR is a low-density lipoprotein receptor (LDLR) family member and a less well characterized low-density lipoprotein (LDL) receptor. It is believed to serve as an alternative or “backup” receptor to the canonical LDLR for Apolipoprotein B (ApoB)-containing lipoproteins in lipid metabolism, but it's exact physiological role and contribution to lipoprotein metabolism remains to be determined. It may also be involved in lipid clearance in specific tissues or under certain metabolic conditions. The continued discovery and characterization of this novel lipoprotein receptor is an active area of cardiovascular research.

Alternative Names

APOBR proto-oncogene; ret proto-oncogene; Ret; PTC; APOBR51; APOBR9; c-Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; APOBR-ELE1.

Background

Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis.

Anti-APOBR rAb Products

Anti-APOBR recombinant antibodies are designed with high specificity to distinguish APOBR from the closely related LDLR and other members of the LDLR family. Distinguishing this new receptor and its true contribution to lipid metabolism requires an antibody with this level of precision for studies on receptor expression and function. Validated for a wide range of robust applications, our rAbs will give you clean, unambiguous results and you can rely on them to get to the bottom of this new receptor.

Table 1. Featured anti-APOBR recombinant antibody products at Creative Biolabs.

Customer Reviews

rAb Production

Creative Biolabs has adopted and leveraged the most advanced recombinant antibody production technologies for novel pathway research. Anti-APOBR recombinant antibodies are expressed in advanced mammalian cell lines for appropriate folding and post-translational modifications necessary for recognizing the native structure of the receptor. This ensures the production of a highly specific and active antibody for your discovery research.

Featured Anti-APOBR Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-APOBR recombinant antibody production.

Fig.2 Gram-scale anti-APOBR recombinant antibody production.

rAb Modalities

Creative Biolabs is focused on supporting your research and scientific discoveries by providing high quality and flexible antibody solutions. Anti-APOBR recombinant antibodies are available in a variety of customizable formats to meet your diverse experimental needs, whether you require full-length IgGs for receptor uptake assays, smaller antibody fragments or you are working in another species, we can customize the right antibody for you. Help power your research and work from anywhere in the world with Creative Biolabs.

Fig.3 Full-length anti-APOBR recombinant antibody production and modalities.

Stay on the cutting edge of lipid metabolism research with Creative Biolabs' highly specific anti-APOBR recombinant antibodies. Our portfolio of research tools is designed with the precision and reliability you need to study this novel lipoprotein receptor. Place your trust in our quality to give your research a strong foundation. Contact our expert team today to find out more about our unique products.