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ATOH7
This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011]
Protein class
Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cone photoreceptor cells, Excitatory neurons, Hepatocytes, Spermatogonia)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (SCLC-21H)
Interaction
Forms a heterodimer with TCF3 isoform E47; interaction may be required for DNA-binding in certain situations.
Molecular function
Developmental protein, DNA-binding
More Types Infomation
- Mouse Anti-ATOH7 Recombinant Antibody (clone EML951) (MOB-1216CT)
-
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB
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For Research Use Only. Not For Clinical Use.