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AVPR1A
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]
Protein class
FDA approved drug targets, G-protein coupled receptors, Plasma proteins
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Smooth muscle cells, Sertoli cells, Hepatocytes, Endometrial stromal cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (ASC diff, Karpas-707, U-266/84)
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgM
- Application: WB
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For Research Use Only. Not For Clinical Use.