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APOBR

Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Distal enterocytes, Paneth cells, NK-cells, Undifferentiated cells, Intestinal goblet cells, granulocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HEL, HMC-1, NB-4, THP-1, U-937)

Interaction

Homodimer.

Molecular function

Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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