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ARHGEF5

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Distal enterocytes, Paneth cells, Glandular and luminal cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (A-431, CAPAN-2, HaCaT, hTCEpi, RPTEC TERT1, WM-115)

Interaction

Interacts with SRC (By similarity). Forms a ternary complex with SRC and the PI3K 85 kDa subunit (By similarity). Interacts with and is activated by the heterodimer formed by GNB1 and GNG2 (By similarity). Interacts with ODAM (via C-terminus) (PubMed:25911094). Interacts with RHOA (By similarity).

Molecular function

Guanine-nucleotide releasing factor

More Types Infomation

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