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BAG5
Anti-BAG5 Recombinant Antibody Products
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- Anti-BAG5 Immunohistochemistry Kit (VS-0325-XY221)
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- Species Reactivity: Human, Mouse, Rat
- Target: BAG5
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.
Predicted location
Intracellular
Single cell type specificity
Group enriched (Late spermatids, Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Binds to the ATPase domain of HSP/HSC70 chaperones. Binds PRKN.
Molecular function
Chaperone
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