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BAIAP2L1

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For Research Use Only. Not For Clinical Use.


Background

May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Urothelial cells, Prostatic glandular cells, Gastric mucus-secreting cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (SK-BR-3)

Interaction

Interacts with RAC1. Binds to F-actin. Interacts with FASLG. Interacts (via SH3 domain) with E.coli effector protein EspF(U) (via PXXP motifs). Identified in a complex containing at least WASL, BAIAP2L1 and E.coli EspF(U). Interacts with E.coli intimin receptor Tir.

Molecular function

Actin-binding

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