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BCAP31
Loading...Anti-BCAP31 Products
- Mouse Anti-BCAP31 Recombinant Antibody (VS3-FY2631) (VS3-FY2631)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: WB, IHC
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- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB, IHC, IF, FC
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- Mouse Anti-BCAP31 Recombinant Antibody (VS3-CJ1018) (VS3-CJ1018)
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IHC
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- Rabbit Anti-BCAP31 Recombinant Antibody (clone JG37-81) (MRO-0154-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- A*02:01/Human BCAP31 (KLDVGNAEV) MHC Tetramer (MHC-CN0404)
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- Class: Class I
- Antigen: BCAP31
- Antigen Species: Human
- Peptide: KLDVGNAEV
- Conjugate: Unconjugated
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- FITC-A*02:01/Human BCAP31 (KLDVGNAEV) MHC Tetramer (MHC-CN0403)
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- Class: Class I
- Antigen: BCAP31
- Antigen Species: Human
- Peptide: KLDVGNAEV
- Conjugate: FITC
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- APC-A*02:01/Human BCAP31 (KLDVGNAEV) MHC Tetramer (MHC-CN0402)
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- Class: Class I
- Antigen: BCAP31
- Antigen Species: Human
- Peptide: KLDVGNAEV
- Conjugate: APC
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- PE-A*02:01/Human BCAP31 (KLDVGNAEV) MHC Tetramer (MHC-CN0401)
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- Class: Class I
- Antigen: BCAP31
- Antigen Species: Human
- Peptide: KLDVGNAEV
- Conjugate: PE
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- Anti-BCAP31 Immunohistochemistry Kit (VS-0325-XY226)
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- Species Reactivity: Human
- Target: BCAP31
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012]
Protein class
Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer and heterodimer with BCAP29 (PubMed:9334338, PubMed:23967155). Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1 (PubMed:9334338, PubMed:11917123, PubMed:31206022). Forms a complex (via C-terminus) with TOMM40 which mediates the translocation of components of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) from the cytosol to the mitochondria; within the complex BCAP31 interacts directly with unprocessed and processed NDUFS4 and NDUFB11 (PubMed:31206022). Interacts with VDAC1 (PubMed:31206022). Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins (By similarity). Interacts with HACD2 (PubMed:15024066). (Microbial infection) Interacts (via C-terminus) with HRSV membrane protein SH; this interaction is direct.
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