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BCL9
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq, Jul 2008]
Protein class
Cancer-related genes, Disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Astrocytes, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (NTERA-2)
Interaction
Binds to beta-catenin (CTNNB1), PYGO1 and PYGO2; the interaction with PYGO1 increases PYGO1 affinity to histone H3 methylated at 'Lys 4'.
More Types Infomation
Related Signaling Pathways
Canonical Wnt Signaling Pathway
Non-Canonical Wnt Signaling Pathway
- Mouse Anti-BCL9 Recombinant Antibody (clone EML208) (MOB-0249CT)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, IF, WB
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For Research Use Only. Not For Clinical Use.