BCL9

Formats

Anti-BCL9 Recombinant Antibody Products

Mouse Anti-BCL9 Recombinant Antibody (clone EML208) (MOB-0249CT)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, IF, WB
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For Research Use Only. Not For Clinical Use.

BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq, Jul 2008]

Protein class

Cancer-related genes, Disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Astrocytes, Oligodendrocyte precursor cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (NTERA-2)

Interaction

Binds to beta-catenin (CTNNB1), PYGO1 and PYGO2; the interaction with PYGO1 increases PYGO1 affinity to histone H3 methylated at 'Lys 4'.