Plasma proteins
Intracellular
Cell type enhanced (Suprabasal keratinocytes, Prostatic glandular cells, Basal keratinocytes, Basal squamous epithelial cells)
Group enriched (basophil, neutrophil)
Cell line enhanced (HHSteC, NB-4)
Interacts with MCL1 and BCL2A1 (By similarity). Interacts (via BH3 domain) with BCL2 (PubMed:11463391). Interacts with BCL2L1/BCL-XL (PubMed:23340338). Interacts (via BH3 domain) with NOL3/ARC (via CARD domain); this interaction prevents BBC3 association with BCL2 and results in CASP8 activation (By similarity).
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For Research Use Only. Not For Clinical Use.