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C6orf25

This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class

Disease related genes

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enriched (granulocytes)

Immune cell specificity

Immune cell enhanced (NK-cell)

Cell line specificity

Cell line enriched (HEL)

Interaction

Interacts (via ITIM motif) with PTPN6 and PTPN11 (PubMed:11544253, PubMed:23112346). Binds to heparin (PubMed:15848171).

Molecular function

Heparin-binding, Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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