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CD22
CD22 (CD22 Molecule) is a Protein Coding gene. Diseases associated with CD22 include Refractory Hematologic Cancer and Refractory Hairy Cell Leukemia. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is SIGLEC1.
- Recombinant Anti-Human CD22 Antibody scFv Fragment (MOB-1248z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IF, FuncS
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- Recombinant Anti-Human CD22 Antibody Fab Fragment (MOB-1248z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, RIA, FuncS
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- Anti-Human CD22 Recombinant Antibody Fab Fragment (CD22.1) (TAB-1721CL-F(E))
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- Type: Human antibody
- Application: ELISA, FC, FuncS
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- Anti-Human CD22 Recombinant Antibody Fab Fragment (21F6) (TAB-1720CL-F(E))
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- Derivation: Human
- Type: Fully human antibody
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- Anti-Human CD22 Recombinant Antibody Fab Fragment (4G6) (TAB-1719CL-F(E))
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- Derivation: Human
- Type: Fully human antibody
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- Anti-Human CD22 Recombinant Antibody Fab Fragment (23C6) (TAB-1718CL-F(E))
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- Derivation: Human
- Type: Fully human antibody
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- Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-001LC-S(P)) (TAB-001LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Anti-CD22 (clone 10F4v3)-MC-vc-PAB-MMAE ADC (ADC-230CL)
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- Target: CD22
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
Compare
- Anti-CD22 (clone 10F4v1)-MC-MMAF ADC (ADC-229CL)
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- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
Compare
- Anti-CD22 (clone 10F4v3)-MC-vc-PAB-MMAE ADC (ADC-228CL)
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- Target: CD22
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
Compare
- Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1724CL-S(P)) (TAB-1724CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Inhib
Compare
- Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1723CL-S(P)) (TAB-1723CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Inhib
Compare
- Anti-Human CD22 Recombinant Antibody scFv Fragment (CD22.2) (TAB-1722CL-S(P))
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- Type: Human antibody
- Application: ELISA, FC, FuncS
Compare
- Anti-Human CD22 Recombinant Antibody scFv Fragment (CD22.1) (TAB-1721CL-S(P))
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- Type: Human antibody
- Application: ELISA, FC, FuncS
Compare
- Anti-Human CD22 Recombinant Antibody scFv Fragment (21F6) (TAB-1720CL-S(P))
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- Derivation: Human
- Type: Fully human antibody
Compare
- Human Anti-CD22 Recombinant Antibody (TAB-001LC) (TAB-001LC)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
Compare
- Human Anti-CD22 Recombinant Antibody (TAB-1729CL) (TAB-1729CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: IF, FC
Compare
- Anti-Human CD22 Recombinant Antibody (RFB4) (TAB-1728CL)
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- Application: IF, FC
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- Human Anti-CD22 Recombinant Antibody (TAB-1725CL) (TAB-1725CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: Block, Cyt, ELISA, FuncS
Compare
- Human Anti-CD22 Recombinant Antibody (TAB-1724CL) (TAB-1724CL)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: Inhib
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- Anti-Human CD22 Recombinant Antibody Fab Fragment (16F7) (TAB-1717CL-F(E))
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- Derivation: Human
- Type: Fully human antibody
Compare
- Anti-Human CD22 Recombinant Antibody Fab Fragment (19A3) (TAB-1716CL-F(E))
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- Derivation: Human
- Type: Fully human antibody
Compare
- Anti-Human CD22 Recombinant Antibody Fab Fragment (12C5) (TAB-1715CL-F(E))
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- Derivation: Human
- Type: Fully human antibody
Compare
- Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1714CL-F(E)) (TAB-1714CL-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
Compare
- Anti-Human CD22 Recombinant Antibody Fab Fragment (hLL2-Cys) (TAB-0197CL-F(E))
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- Application: ELISA, In vivo
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- Anti-Human CD22 Recombinant Antibody scFv Fragment (4G6) (TAB-1719CL-S(P))
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- Derivation: Human
- Type: Fully human antibody
Compare
- Anti-Human CD22 Recombinant Antibody scFv Fragment (23C6) (TAB-1718CL-S(P))
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- Derivation: Human
- Type: Fully human antibody
Compare
- Anti-Human CD22 Recombinant Antibody scFv Fragment (16F7) (TAB-1717CL-S(P))
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- Derivation: Human
- Type: Fully human antibody
Compare
- Anti-Human CD22 Recombinant Antibody scFv Fragment (19A3) (TAB-1716CL-S(P))
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- Derivation: Human
- Type: Fully human antibody
Compare
- Anti-Human CD22 Recombinant Antibody scFv Fragment (12C5) (TAB-1715CL-S(P))
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- Derivation: Human
- Type: Fully human antibody
Compare
- Anti-Human CD22 Recombinant Antibody (CD22.2) (TAB-1722CL)
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- Type: Human antibody
- Application: ELISA, FC, FuncS
Compare
- Anti-Human CD22 Recombinant Antibody (CD22.1) (TAB-1721CL)
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- Type: Human antibody
- Application: ELISA, FC, FuncS
Compare
- Anti-Human CD22 Recombinant Antibody (21F6) (TAB-1720CL)
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- Derivation: Human
- Type: Fully human antibody
- Application: ELISA
Compare
- Anti-Human CD22 Recombinant Antibody (4G6) (TAB-1719CL)
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- Derivation: Human
- Type: Fully human antibody
- Application: ELISA
Compare
- Anti-Human CD22 Recombinant Antibody (23C6) (TAB-1718CL)
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- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
Compare
- Anti-CD22 (clone RFB4)-MC-vc-PAB-MMAE ADC (ADC-227CL)
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- Target: CD22
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
Compare
- Anti-CD22 (clone RFB4)-MC-MMAF ADC (ADC-226CL)
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- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
Compare
- Anti-CD22 (clone RFB4)-MC-vc-PAB-MMAF ADC (ADC-225CL)
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- Target: CD22
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAF (Monomethyl auristatin F)
Compare
- Anti-CD22 (clone RFB4)-SMCC-DM1 ADC (ADC-224CL)
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- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
- Anti-CD22 (clone 10F4)-SMCC-DM1 ADC (ADC-223CL)
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- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
- Anti-Human CD22 Recombinant Antibody Fab Fragment (hLL2) (TAB-0196CL-F(E))
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- Application: ELISA, In vivo
Compare
- Anti-Human CD22 Recombinant Antibody scFv Fragment (hLL2-Cys) (TAB-0197CL-S(P))
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- Application: ELISA, In vivo
Compare
- Anti-Human CD22 Recombinant Antibody scFv Fragment (hLL2) (TAB-0196CL-S(P))
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- Application: ELISA, In vivo
Compare
- Anti-CD22 (CR011)-vc-MMAE ADC (RG7593) (ADC-L028)
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- Target: CD22
- Linker: vc (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
Compare
- Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1714CL-S(P)) (TAB-1714CL-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB
Compare
- Anti-Human CD22 Recombinant Antibody (hLL2-Cys) (TAB-0197CL)
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- Application: ELISA, In vivo
Compare
- Anti-Human CD22 Recombinant Antibody (hLL2) (TAB-0196CL)
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- Application: Inhib, Cyt, FC, WB
Compare
- Anti-CD22 (clone 10F4v3)-mc-MMAF ADC (ADC-196LZY)
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- Target: CD22
- Linker: mc(maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
Compare
- Anti-CD22 (clone 10F4v3)-mc-vc-PABC-MMAE ADC (ADC-195LZY)
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- Target: CD22
- Linker: mc-VC-PABC(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
Compare
- Anti-Human CD22 Recombinant Antibody (16F7) (TAB-1717CL)
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- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
Compare
- Anti-Human CD22 Recombinant Antibody (19A3) (TAB-1716CL)
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- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
Compare
- Anti-Human CD22 Recombinant Antibody (12C5) (TAB-1715CL)
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- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
Compare
- Mouse Anti-CD22 Recombinant Antibody (TAB-1714CL) (TAB-1714CL)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB
Compare
- Anti-CD22 (Inotuzumab)-DIBO-doxorubicin ADC (ADC-037LCT)
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- Target: CD22
- Linker: DIBO (dibenzylcyclooctynol)
- Drug: doxorubicin
Compare
- Anti-CD22 (clone 10F4v3)-MC-vc-PAB-MMAE ADC (ADC-222CL)
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- Target: CD22
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
Compare
- Anti-CD22 (clone 10F4v3)-SPP-DM1 ADC (ADC-221CL)
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- Target: CD22
- Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
- Anti-CD22 (clone 10F4v3)-MC-MMAF ADC (ADC-220CL)
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- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
Compare
- Anti-CD22 (clone 10F4v3)-SMCC-DM1 ADC (ADC-219CL)
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- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
- Anti-CD22 (clone 10F4v2)-MC-MMAF ADC (ADC-218CL)
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- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
Compare
- Anti-CD22 (Inotuzumab)-hydrazone-Calicheamicin ADC (ADC-036LCT)
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- Target: CD22
- Linker: hydrazone
- Drug: Calicheamicin
Compare
- Anti-CD22 (Pinatuzumab)-MC-VC-PABC-MMAE ADC (ADC-034LCT)
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- Target: CD22
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
Compare
- Anti-CD22-MCC-DM1 ADC (ADC-033LCT)
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- Target: CD22
- Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
- Anti-CD22-MC-MMAF ADC (ADC-032LCT)
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- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
Compare
- Anti-CD22-CL2E-SN-38 ADC (ADC-031LCT)
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- Target: CD22
- Linker: CL2E
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
Compare
- Anti-CD22-mc-vc-PABc-MMAE ADC (ADC-033LZY)
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- Target: CD22
- Linker: mc-VC-PABc(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
Compare
- Anti-CD22 (clone hu10F4)-MCC-DM1 ADC (ADC-027LZY)
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- Target: CD22
- Linker: MCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
Compare
- Anti-CD22-AcBut-CalichDMH ADC (ADC-006LZY)
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- Target: CD22
- Linker: AcBut (4-(4-acetylphenoxy)butanoic acid)
- Drug: CalichDMH
Compare
- Anti-CD22 (clone G5/44)-AcBut-CalichDMH ADC (ADC-003LZY)
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- Target: CD22
- Linker: AcBut (4-(4-acetylphenoxy)butanoic acid)
- Drug: CalichDMH
Compare
- anti-CD22 immunotoxin RFB4 (scFv)-Sap (AGTO-L048S)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
Compare
- Anti-CD22 (clone 10F4v3)-MCC-DM1 ADC (ADC-194LZY)
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- Target: CD22
- Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
Compare
- Anti-CD22 (clone 10F4v3)-SPP-DM1 ADC (ADC-193LZY)
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- Target: CD22
- Linker: SPP(N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
Compare
- Anti-CD22 (clone HB22.7)-saporin ADC (ADC-154LZY)
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- Target: CD22
- Drug: saporin
Compare
- Anti-CD22-mc-vc-PABc-NMS249 ADC (ADC-097LZY)
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- Target: CD22
- Linker: mc-VC-PABc (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: NMS249
Compare
- Anti-CD22 immunotoxin RFB4 (IgG)-Sap (AGTO-G077S)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
Compare
- Anti-CD22 (clone 10F4v2)-SMCC-DM1 ADC (ADC-217CL)
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- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
- Anti-CD22 (clone 10F4v1)-SMCC-DM1 ADC (ADC-216CL)
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- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
- Anti-CD22 (clone 7A2)-SMCC-DM1 ADC (ADC-215CL)
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- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
- Anti-CD22 (clone 5E8)-SMCC-DM1 ADC (ADC-214CL)
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- Target: CD22
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
- Anti-CD22-CL2A-SN-38 ADC (ADC-030LCT)
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- Target: CD22
- Linker: CL2A
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
Compare
- Anti-CD22 (10F4)-AcBut-Calicheamicin ADC (ADC-029LCT)
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- Target: CD22
- Linker: AcBut
- Drug: Calicheamicin
Compare
- Anti-CD22 (RFB4)-mcc-DM1 ADC (ADC-028LCT)
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- Target: CD22
- Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
- Anti-CD22 (clone hLL2)-SN-38 ADC (ADC-124CL)
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- Target: CD22
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
Compare
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab' - G2a - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Compare
- Anti-CD22 (clone 10F4v3)-MC-vc-PAB-MMAE ADC (ADC-213CL)
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- Target: CD22
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
Compare
- Anti-CD22 (clone 10F4v3)-MC-MMAF ADC (ADC-212CL)
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- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
Compare
- Anti-CD22 (clone 10F4v3)-BMPEO-DM1 ADC (ADC-211CL)
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- Target: CD22
- Linker: BMPEO (bis-maleimido-trioxyethylene glycol)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
Compare
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG1, κ
- Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Compare
- anti-CD22 immunotoxin RFB4 (scFv)-RTA (AGTO-L048R)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
Compare
- anti-CD22 immunotoxin RFB4 (scFv)-Gel (AGTO-L048G)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
Compare
- anti-CD22 immunotoxin RFB4 (scFv)-DT (AGTO-L048D)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
Compare
- anti-CD22 immunotoxin RFB4 (scFv)-PE (AGTO-L048E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
Compare
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG4, κ
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Compare
- Anti-CD22 immunotoxin RFB4 (IgG)-RTA (AGTO-G077R)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
Compare
- Anti-CD22 immunotoxin RFB4 (IgG)-Gel (AGTO-G077G)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
Compare
- Anti-CD22 immunotoxin RFB4 (IgG)-DT (AGTO-G077D)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
Compare
- Anti-CD22 immunotoxin RFB4 (IgG)-PE (AGTO-G077E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
Compare
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Compare
- Anti-Human CD22 Recombinant Antibody (Moxetumomab Pasudotox) (TAB-183-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fv - disulfide stabilized
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Compare
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