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CD22
Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome.
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IF, FC
- Recombinant Anti-Human CD22 Antibody scFv Fragment (MOB-1248z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IF, FuncS
- Recombinant Anti-Human CD22 Antibody Fab Fragment (MOB-1248z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, RIA, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab' - G2a - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, WB
- Anti-Human CD22 Recombinant Antibody (Moxetumomab Pasudotox) (TAB-183-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fv - disulfide stabilized
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
- Anti-CD22 immunotoxin RFB4 (IgG)-RTA (AGTO-G077R)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
- Anti-CD22 (10F4)-AcBut-Calicheamicin ADC (ADC-029LCT)
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- Target: CD22
- Linker: AcBut
- Drug: Calicheamicin
- Anti-CD22 (clone 10F4v3)-MC-MMAF ADC (ADC-212CL)
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- Target: CD22
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- anti-CD22 immunotoxin RFB4 (scFv)-Gel (AGTO-L048G)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
- Anti-CD22 immunotoxin RFB4 (IgG)-Gel (AGTO-G077G)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
- Anti-CD22 (RFB4)-mcc-DM1 ADC (ADC-028LCT)
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- Target: CD22
- Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- anti-CD22 immunotoxin RFB4 (scFv)-DT (AGTO-L048D)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
- Anti-CD22 (clone 10F4v3)-BMPEO-DM1 ADC (ADC-211CL)
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- Target: CD22
- Linker: BMPEO (bis-maleimido-trioxyethylene glycol)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CD22 immunotoxin RFB4 (IgG)-DT (AGTO-G077D)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
- Anti-CD22 (clone hLL2)-SN-38 ADC (ADC-124CL)
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- Target: CD22
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
- anti-CD22 immunotoxin RFB4 (scFv)-PE (AGTO-L048E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
- Anti-CD22 immunotoxin RFB4 (IgG)-PE (AGTO-G077E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
- Anti-CD22 immunotoxin RFB4 (IgG)-Sap (AGTO-G077S)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG1, κ
- Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
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