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CD22

Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome.
  • Anti-CD22 (clone 10F4v3)-SMCC-DM1 ADC (ADC-219CL)

    • Target: CD22
    • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
    • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
  • Anti-CD22 (RFB4)-mcc-DM1 ADC (ADC-028LCT)

    • Target: CD22
    • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
    • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
  • Anti-CD22 (clone 10F4v2)-SMCC-DM1 ADC (ADC-217CL)

    • Target: CD22
    • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
    • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
  • Anti-CD22 (clone 10F4v1)-SMCC-DM1 ADC (ADC-216CL)

    • Target: CD22
    • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
    • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
  • Anti-CD22 (clone 7A2)-SMCC-DM1 ADC (ADC-215CL)

    • Target: CD22
    • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
    • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)

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