CD22
Anti-CD22 Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fv - disulfide stabilized
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG4, κ
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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- Type: Human antibody
- Application: ELISA, FC, FuncS
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- Type: Human antibody
- Application: ELISA, FC, FuncS
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- Derivation: Human
- Type: Fully human antibody
- Application: ELISA
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- Derivation: Human
- Type: Fully human antibody
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FC, Cyt, Block, Apop, ROS assay, FuncS
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- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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- Application: Inhib, Cyt, FC, WB
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- Type: Human antibody
- Application: ELISA, FC, FuncS
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- Type: Human antibody
- Application: ELISA, FC, FuncS
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- Derivation: Human
- Type: Fully human antibody
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- Derivation: Human
- Type: Fully human antibody
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- Derivation: Human
- Type: Fully human antibody
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- Application: ELISA, In vivo
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- Application: ELISA, In vivo
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- Type: Human antibody
- Application: ELISA, FC, FuncS
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- Derivation: Human
- Type: Fully human antibody
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- Derivation: Human
- Type: Fully human antibody
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- Derivation: Human
- Type: Fully human antibody
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- Derivation: Human
- Type: Fully human antibody
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- Derivation: Human
- Type: Fully human antibody
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- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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- Derivation: Human
- Type: Fully human antibody
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- Application: ELISA, In vivo
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- Type: Human antibody
- Application: ELISA, FC, FuncS
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- Derivation: Human
- Type: Fully human antibody
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- Derivation: Human
- Type: Fully human antibody
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- Derivation: Human
- Type: Fully human antibody
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- Application: ELISA, In vivo
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- Application: ELISA, In vivo
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: IF, FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: Block, Cyt, ELISA, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: Block, Cyt, ELISA, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: IF, FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: IF, FC
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- Derivation: Humanized
- Type: Humanized antibody
- Application: FC, ELISA, SPR, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: Block, Cyt, ELISA, FuncS
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, SPR
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG1, κ
- Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, SPR
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: Inhib
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: Inhib
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Inhib
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Inhib
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Inhib
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab' - G2a - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IP, WB
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For Research Use Only. Not For Clinical Use.
CD22 is a B-cell-specific transmembrane glycoprotein belonging to the SIGLEC (sialic acid-binding immunoglobulin-like lectin) family. It is encoded by the CD22 gene located on chromosome 19q13.1. CD22 plays a crucial role in B-cell signaling and immune response modulation. It acts primarily as an inhibitory co-receptor that regulates B-cell receptor (BCR) signaling, thereby preventing overactivation of B cells and reducing the risk of autoimmunity. CD22 binds to sialylated glycans and recruits SHP-1 (Src homology region 2 domain-containing phosphatase-1), a phosphatase that dampens signaling cascades.