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CD33

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CD33 (CD33 Molecule) is a Protein Coding gene. Diseases associated with CD33 include Gallbladder Lymphoma and Extracutaneous Mastocytoma. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include receptor activity and carbohydrate binding. An important paralog of this gene is SIGLEC6.

Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
IgG4 kappa
Application:
IF, IP, Neut, FuncS, ELISA, FC, WB
Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, FC, IP, FuncS, IF, Neut, IHC
Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
IF, IP, Neut, FuncS, ELISA, FC, ICC
Target:
CD33
Linker:
AcBut
Drug:
Calicheamicin
Target:
CD33
Linker:
DOTA-G3FC
Target:
CD33
Linker:
DOTA-NCS
Target:
CD33
Linker:
DOTA-SH
Target:
CD33
Linker:
hydrazone
Drug:
Calicheamicin
Target:
CD33
Linker:
SPDB
Drug:
DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
Target:
CD33
Linker:
mc-VC (maleimidocaproyl-valine-citrulline)
Drug:
pyrrolobenzodiazepine (PBD) dimers
Target:
CD33
Linker:
VC-PABC (valine-citrulline-p-aminobenzoyloxycarbonyl)
Drug:
MMAE (Monomethyl auristatin E)
Target:
CD33
Linker:
AcBut (4-(4-acetylphenoxy)butanoic acid)
Drug:
Calicheamicin
Target:
CD33
Linker:
SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
Drug:
DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
Target:
CD33
Linker:
mc-VC (maleimidocaproyl-valine-alanine)
Drug:
pyrrolobenzodiazepine (PBD) dimers
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, IP, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
WB, ELISA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
IF, FC, Biosensors, FuncS
Species Reactivity:
Human
Application:
Cytotoxicity assay, Functional assay
Species Reactivity:
Human
Application:
Cytotoxicity assay, Functional assay
Target:
CD33
Linker:
acetyl butyrate linker
Drug:
calicheamicin
Target:
CD33
Linker:
mc-vc (maleimidocaproyl-valine-alanine)
Drug:
pyrrolobenzodiazepine (PBD) dimers SGD-1882