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CD70
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, IF, IHC, IP
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, FC, FuncS, IHC-Fr, IP
- Rat Anti-Cd70 Recombinant Antibody (clone 9G24) (NEUT-403CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: ELISA, Neut
- Rat Anti-Cd70 Recombinant Antibody (clone MAB0825) (NEUT-404CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2
- Application: Block, FC, Inhib, IP
- Rat Anti-Cd70 Recombinant Antibody (clone CBL684) (NEUT-405CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: ELISA, Neut
- Rat Anti-Cd70 Recombinant Antibody (clone FR70) (NEUT-406CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: FC, FuncS, Neut, IP
- Rat Anti-Cd70 Recombinant Antibody (clone CBL856) (NEUT-407CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: ELISA, Neut
- Human Anti-CD70 Recombinant Antibody (MOB-072LC) (MOB-072LC)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC, FuncS
- Anti-CD27L-DM1 ADC (ADC-127LZY)
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- Target: CD27L
- Linker: Noncleavable thioether linker
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD70 (1F6)-C4v2-mc-vc-MMAF ADC (ADC-069LCT)
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- Target: CD70
- Linker: mc-VC (maleimidocaproyl-valine-citrulline)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD27L-MCC-DM1 ADC (ADC-038LZY)
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- Target: CD27L
- Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD70 (clone 2F2)-vc-AFP ADC (ADC-115CL)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: AFP (dimethylvaline-valine-dolaisoleuine-dolaproine-phenylalanine-p-phenylenediamine)
- Anti-CD70 (clone h1F6)-MCC-DM1 ADC (ADC-052LZY)
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- Target: CD70
- Linker: MCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD70 (clone h1F6)-mc-MMAF ADC (ADC-036LZY)
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- Target: CD70
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
- Anti-CD70 (clone 2F2)-vc-MMAE ADC (ADC-114CL)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD70 (1F6)-C4v2-mc-MMAF ADC (ADC-068LCT)
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- Target: CD70
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD70 (clone h1F6)-vc-PABC-MMAF ADC (ADC-051LZY)
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- Target: CD70
- Linker: VC-PABC(valine-citrulline-p-aminobenzylcarbamate)
- Drug: MMAF (monomethyl auristatin F)
- Anti-CD70-vc-MGBA ADC (ADC-014LZY)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MGBA
- Anti-CD70 (clone 1F6)-vc-MMAF ADC (ADC-113CL)
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- Target: CD70
- Linker: VC (valine-citrulline)
- Drug: MMAF (Monomethyl auristatin F)
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For Research Use Only. Not For Clinical Use.