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    CD79b & CD3

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    Anti-CD79b & CD3 Products

    • Anti-cyCD79b (clone 10D10)-MCC-DM1 ADC (ADC-216LZY)
      • Target: cyCD79b
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate))
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b-MCC-DM1 ADC (ADC-084LZY)
      • Target: CD79b
      • Linker: MCC (4-(Nmaleimidomethyl)cyclohexane-1 carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b-mc-MMAF ADC (ADC-085LZY)
      • Target: CD79b
      • Linker: mc(maleimidocaproyl)
      • Drug: MMAF(monomethyl auristatin F)
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    • Anti-CD79b (clone SN8)-SPP-DM1 ADC (ADC-201LZY)
      • Target: CD79b
      • Linker: SPP(N-succinimidyl-4-(2-pyridyldithio)pentanoate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b (clone SN8)-MCC-DM1 ADC (ADC-202LZY)
      • Target: CD79b
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79 (bSN8)-mcc-DM1 ADC (ADC-089LCT)
      • Target: CD79b
      • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD79b-vc-MMAE ADC (ADC-034LZY)
      • Target: CD79b
      • Linker: VC(Valine-citrulline)
      • Drug: MMAE (monomethyl auristatin E)
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    • Anti-CD79b (clone ch2F2)-SMCC-DM1 ADC (ADC-202CL)
      • Target: CD79b
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD79b (clone hu2F2.D7)-SMCC-DM1 ADC (ADC-203CL)
      • Target: CD79b
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    For Research Use Only. Not For Clinical Use.


    Background

    CD79B (CD79b Molecule) is a Protein Coding gene. Diseases associated with CD79B include Agammaglobulinemia 6, Autosomal Recessive and Agammaglobulinemia, Non-Bruton Type. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity.
    CD79b & CD3
    The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
    Related Signaling Pathways
    BCR Signaling Pathway BCR Signaling Pathway
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