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CD79b & CD3
Loading...Anti-CD79b & CD3 Products
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG1, κ
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
- Mouse Anti-CD3 Recombinant Antibody (TAB-0416CL) (TAB-0416CL)
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- Application: FC, IB, ELISA
- Mouse Anti-CD3 Recombinant Antibody Fab Fragment (TAB-0416CL-F(E)) (TAB-0416CL-F(E))
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- Application: IB, ELISA, FC, FuncS
- Mouse Anti-CD3 Recombinant Antibody scFv Fragment (TAB-0416CL-S(P)) (TAB-0416CL-S(P))
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- Application: IB, ELISA, FC, FuncS
- Humanized Anti-Human CD3 Recombinant Antibody (TAB-0418CL)
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- Type: Humanized Antibody
- Application: ELISA, FC, FuncS
- Human Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-0532CL-S(P))
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- Type: Human antibody
- Rat Anti-CD3 Recombinant Antibody (clone 17A2) (MOB-0202MC)
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- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: FC, IHC, IP, Activ, CMCD, Depletion
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC, FuncS
- Humanized Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-0418CL-F(E))
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- Type: Humanized Antibody
- Application: ELISA, FC, FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Fab fragment
- Application: ELISA
- Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-072LC-S(P))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
- Human Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-0532CL-F(E))
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- Type: Human antibody
- Anti-Human CD3 Recombinant Antibody (TAB-071LC)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
- Chimeric Anti-Human CD3 Recombinant Antibody (TAB-072LC)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
- Human Anti-Human CD3 Recombinant Antibody (TAB-0532CL)
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- Type: Human antibody
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-075LC-S(P)) (TAB-075LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-076LC-S(P)) (TAB-076LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-077LC-S(P)) (TAB-077LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
- Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-071LC-F(E))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
- Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-072LC-F(E))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (TAB-075LC) (TAB-075LC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (TAB-076LC) (TAB-076LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-077LC) (TAB-077LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-078LC) (TAB-078LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-079LC) (TAB-079LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-080LC) (TAB-080LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-081LC) (TAB-081LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (TAB-083LC) (TAB-083LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (TAB-084LC) (TAB-084LC)
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- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
- Anti-Human CD3 Recombinant Antibody (TAB-085LC) (TAB-085LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
- Anti-Human CD3 Recombinant Antibody (TAB-086LC) (TAB-086LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-087LC) (TAB-087LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-088LC) (TAB-088LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-089LC) (TAB-089LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
- Anti-Human CD3 Recombinant Antibody (TAB-090LC) (TAB-090LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-075LC-F(E)) (TAB-075LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-076LC-F(E)) (TAB-076LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-077LC-F(E)) (TAB-077LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-078LC-F(E)) (TAB-078LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-079LC-F(E)) (TAB-079LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody (clone SPV-T3b) (NEUT-339CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: FC, Block, IHC-Fr, IF, WB
- Mouse Anti-CD3 Recombinant Antibody (clone UCHT1) (NEUT-340CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, IHC-Fr, IHC-P, ICC, IP, WB, Activ, Block
- PE-A*02:01/Human CD79B (LLSAEPVPA) MHC Tetramer (MHC-LC1918)
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- Class: Class I
- Antigen: CD79B
- Antigen Species: Human
- Peptide: LLSAEPVPA
- Conjugate: PE
- Anti-Human CD3 Recombinant Antibody (TAB-091LC) (TAB-091LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-092LC) (TAB-092LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-093LC) (TAB-093LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0667LY-S(P)) (HPAB-0667LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human, Cynomolgus
- Type: Mouse scfv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0668LY-S(P)) (HPAB-0668LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human, Cynomolgus
- Type: Mouse scfv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0669LY-S(P)) (HPAB-0669LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human, Cynomolgus
- Type: Mouse scfv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0670LY-S(P)) (HPAB-0670LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human, Cynomolgus
- Type: Mouse scfv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0671LY-S(P)) (HPAB-0671LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human, Cynomolgus
- Type: Mouse scfv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0672LY-S(P)) (HPAB-0672LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0673LY-S(P)) (HPAB-0673LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0674LY-S(P)) (HPAB-0674LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0689LY-S(P)) (HPAB-0689LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human, Cynomolgus
- Type: Mouse scfv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0690LY-S(P)) (HPAB-0690LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (TAB-073LC) (TAB-073LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (TAB-074LC) (TAB-074LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Anti-Mouse CD3 Recombinant Antibody scFv Fragment (Dow2) (TAB-0365CL-S(P))
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- Application: IP, IB, FuncS
- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-073LC-F(E)) (TAB-073LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-074LC-F(E)) (TAB-074LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-070LC-F(E)) (TAB-070LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody (TAB-070LC) (TAB-070LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-073LC-S(P)) (TAB-073LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-074LC-S(P)) (TAB-074LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-0422CL-S(P)) (TAB-0422CL-S(P))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-070LC-S(P)) (TAB-070LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-0422CL-F(E)) (TAB-0422CL-F(E))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA
- Anti-Mouse CD3 Recombinant Antibody (Dow2) (TAB-0365CL)
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- Application: FC, IHC
- Anti-Mouse CD3 Recombinant Antibody Fab Fragment (Dow2) (TAB-0365CL-F(E))
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- Application: IP, IB, FuncS
- Mouse Anti-CD3 Recombinant Antibody (TAB-0422CL) (TAB-0422CL)
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA
- Anti-CD79b (SN8)-vc-MMAE ADC (RG7596) (ADC-L029)
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- Target: CD79b
- Linker: vc (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
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- Target: CD79b
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD79b (clone ch10D10)-MC-MMAF ADC (ADC-054CL)
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- Target: CD79b
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD79b (clone ch10D10)-BMPEO-DM1 ADC (ADC-055CL)
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- Target: CD79b
- Linker: BMPEO (bis-maleimido-trioxyethylene glycol)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CD79b (clone ch10D10)-MC-vc-PAB-MMAE ADC (ADC-056CL)
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- Target: CD79b
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD79b (clone MA79b)-MC-MMAF ADC (ADC-057CL)
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- Target: CD79b
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD79b (clone MA79b)-MC-MMAF ADC (ADC-058CL)
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- Target: CD79b
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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- Targets: CD79b & CD3
- Type: Fab2
- Application: FuncS, Promising therapeutic agent
- Anti-CD79b (clone ch2F2)-SMCC-DM1 ADC (ADC-202CL)
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- Target: CD79b
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CD79b (clone huMA79b.v18)-MC-MMAF ADC (ADC-048CL)
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- Target: CD79b
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD79b (clone hu2F2.D7)-SMCC-DM1 ADC (ADC-203CL)
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- Target: CD79b
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CD79b (clone huMA79b.v18)-BMPEO-DM1 ADC (ADC-049CL)
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- Target: CD79b
- Linker: BMPEO (bis-maleimido-trioxyethylene glycol)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CD79b (clone hu2F2.D7)-BMPEO-DMl ADC (ADC-204CL)
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- Target: CD79b
- Linker: BMPEO (bis-maleimido-trioxyethylene glycol)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CD79b (clone huMA79b.v18)-MCvcPAB-MMAE ADC (ADC-050CL)
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- Target: CD79b
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD79b (clone hu2F2.D7)-MC-MMAF ADC (ADC-205CL)
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- Target: CD79b
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD79b (clone huMA79b.v28)-MC-MMAF ADC (ADC-051CL)
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- Target: CD79b
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD79b (clone hu2F2.D7)-MCvcPAB-MMAE ADC (ADC-206CL)
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- Target: CD79b
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD79b (clone huMA79b.v28)-BMPEO-DM1 ADC (ADC-052CL)
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- Target: CD79b
- Linker: BMPEO (bis-maleimido-trioxyethylene glycol)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CD79b (Polatuzumab)-vc-MMAE ADC (ADC-087LCT)
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- Target: CD79b
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD79b-vc-MMAE ADC (ADC-034LZY)
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- Target: CD79b
- Linker: VC(Valine-citrulline)
- Drug: MMAE (monomethyl auristatin E)
- THIO-Anti-CD79b (Polatuzumab)-MC-VC-PABC-MMAE ADC (ADC-088LCT)
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- Target: CD79b
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CD79 (bSN8)-mcc-DM1 ADC (ADC-089LCT)
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- Target: CD79b
- Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CD79b-MCC-DM1 ADC (ADC-084LZY)
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- Target: CD79b
- Linker: MCC (4-(Nmaleimidomethyl)cyclohexane-1 carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD79b-mc-MMAF ADC (ADC-085LZY)
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- Target: CD79b
- Linker: mc(maleimidocaproyl)
- Drug: MMAF(monomethyl auristatin F)
- Anti-CD79b (clone SN8)-SPP-DM1 ADC (ADC-201LZY)
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- Target: CD79b
- Linker: SPP(N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD79b (clone SN8)-MCC-DM1 ADC (ADC-202LZY)
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- Target: CD79b
- Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CD79b (clone SN8)-mc-vc-PABC-MMAE ADC (ADC-203LZY)
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- Target: CD79b
- Linker: mc-VC-PABC(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
- Anti-CD79b (clone SN8)-mc-MMAF ADC (ADC-204LZY)
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- Target: CD79b
- Linker: mc(maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
- Anti-cyCD79b (clone 10D10)-MCC-DM1 ADC (ADC-216LZY)
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- Target: cyCD79b
- Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate))
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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Background
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains.
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component.


BCR Signaling Pathway
