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CD79b & CD3

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Anti-CD79b & CD3 Recombinant Antibody Products

  • Anti-CD79b (clone ch2F2)-SMCC-DM1 ADC (ADC-202CL)
    • Target: CD79b
    • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
    • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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  • Anti-CD79b (clone hu2F2.D7)-SMCC-DM1 ADC (ADC-203CL)
    • Target: CD79b
    • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
    • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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  • Anti-CD79 (bSN8)-mcc-DM1 ADC (ADC-089LCT)
    • Target: CD79b
    • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
    • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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  • Anti-CD79b-vc-MMAE ADC (ADC-034LZY)
    • Target: CD79b
    • Linker: VC(Valine-citrulline)
    • Drug: MMAE (monomethyl auristatin E)
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  • Anti-CD79b-MCC-DM1 ADC (ADC-084LZY)
    • Target: CD79b
    • Linker: MCC (4-(Nmaleimidomethyl)cyclohexane-1 carboxylate)
    • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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  • Anti-CD79b-mc-MMAF ADC (ADC-085LZY)
    • Target: CD79b
    • Linker: mc(maleimidocaproyl)
    • Drug: MMAF(monomethyl auristatin F)
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  • Anti-CD79b (clone SN8)-SPP-DM1 ADC (ADC-201LZY)
    • Target: CD79b
    • Linker: SPP(N-succinimidyl-4-(2-pyridyldithio)pentanoate)
    • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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  • Anti-CD79b (clone SN8)-MCC-DM1 ADC (ADC-202LZY)
    • Target: CD79b
    • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
    • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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  • Anti-cyCD79b (clone 10D10)-MCC-DM1 ADC (ADC-216LZY)
    • Target: cyCD79b
    • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate))
    • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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For Research Use Only. Not For Clinical Use.


Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
CD79b & CD3
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Related Signaling Pathways
BCR Signaling Pathway BCR Signaling Pathway
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