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CD96

The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing generates multiple transcript variants encoding distinct isoforms.
Protein class

CD markers, Disease related genes, Human disease related genes

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (T-cells, dendritic cells, NK-cells)

Immune cell specificity

Group enriched (MAIT T-cell, memory CD8 T-cell, naive CD8 T-cell, NK-cell, gdT-cell, naive CD4 T-cell, memory CD4 T-cell, T-reg)

Cell line specificity

Cell line enhanced (HEL, JURKAT, MOLT-4, RT4, U-937)

Interaction

Homodimer; disulfide-linked. Interacts with PVR.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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