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CDC14B
Anti-CDC14B Recombinant Antibody Products
- Chicken Anti-CDC14b Polyclonal IgY (BRD-0107MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Oligodendrocyte precursor cells, Inhibitory neurons, Astrocytes, Excitatory neurons)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Cell line enhanced (ASC TERT1)
Interaction
Interacts with FZR1/CDH1.
Molecular function
Hydrolase, Protein phosphatase
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