Cancer-related genes, Enzymes, Metabolic proteins
Intracellular
Cell type enhanced (Spermatocytes, Late spermatids, Early spermatids, Spermatogonia)
Not detected in immune cells
Low cell line specificity
Interacts with MAPK14 and 14-3-3 proteins. When phosphorylated on Ser-129 and/or Thr-130, interacts with PLK1. (Microbial infection) Interacts with HIV-1 Vpr; this interaction inactivates CDC25C phosphatase activity.
Hydrolase, Protein phosphatase
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For Research Use Only. Not For Clinical Use.