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CDKN1C

Anti-CDKN1C Products
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG3
- Application: IHC-P
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P, ICC, IF, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgM
- Application: WB
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- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: IHC-P
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- Species Reactivity: Human
- Type: Mouse IgG3, κ
- Application: IHC-P
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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- Type: Mouse IgG1
- Application: ELISA, WB, IHC, FC
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- Type: Mouse IgG1
- Application: ELISA, WB, IHC, FC
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- Species Reactivity: Human
- Application: ELISA, WB
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP, IHC-P, ICC, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
- Anti-CDKN1C Immunohistochemistry Kit (VS-0325-XY413)
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- Species Reactivity: Human
- Target: CDKN1C
- Application: IHC
- Anti-Mouse CDKN1C Immunohistochemistry Kit (VS-0525-XY1338)
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- Species Reactivity: Human, Mouse, Rat
- Target: CDKN1C
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Protein class
Cancer-related genes, Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Extravillous trophoblasts, Theca cells, Cytotrophoblasts)
Immune cell specificity
Group enriched (non-classical monocyte, intermediate monocyte)
Cell line specificity
Cell line enhanced (EFO-21, HeLa, RPMI-8226, SH-SY5Y, SiHa, SK-MEL-30)
Interaction
Interacts with PCNA.
Molecular function
Protein kinase inhibitor
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