+ Filter
Loading...
Custom Services order now ship next day

CDKN1C

Loading...

Anti-CDKN1C Products

More Infomation

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Protein class

Cancer-related genes, Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Syncytiotrophoblasts, Extravillous trophoblasts, Theca cells, Cytotrophoblasts)

Immune cell specificity

Group enriched (non-classical monocyte, intermediate monocyte)

Cell line specificity

Cell line enhanced (EFO-21, HeLa, RPMI-8226, SH-SY5Y, SiHa, SK-MEL-30)

Interaction

Interacts with PCNA.

Molecular function

Protein kinase inhibitor

More Types Infomation
Go to compare

Go to compare