Anti-CEBPB Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs has been a long-term trusted partner in oncology and immunology research and is dedicated to providing our customers with the highest-quality anti-CEBPB recombinant antibodies (rAbs). CCAAT/Enhancer-Binding Protein Beta (CEBPB) is a crucial transcription factor that controls a myriad of cellular processes including differentiation and inflammation, making it a significant player in both normal physiology and disease pathogenesis. Our antibodies serve as indispensable tools for studying the role of CEBPB in cancer progression, immune response regulation, and cellular senescence.

CEBPB: A Master Transcriptional Regulator in Cancer and Inflammation

CCAAT/Enhancer-Binding Protein Beta (CEBPB) is a basic leucine zipper (bZIP) transcription factor critically involved in the normal development and function of many cell types, particularly those in the immune and endocrine systems. Functioning as a key transcriptional driver, it promotes the differentiation of myeloid cells and adipocytes. In the context of disease, CEBPB exhibits a complex, context-dependent function. In certain cancers, CEBPB acts as a pro-oncogenic factor, fueling proliferation and resistance to therapy, as seen in glioblastoma. Conversely, it can also promote cellular senescence and function as a tumor suppressor in other contexts. Central to its role in inflammation, CEBPB is a master regulator of inflammatory gene expression, positioning it as a potential mediator of chronic inflammatory diseases.

Alternative Names

CEBPB; Nuclear Factor Of Interleukin 6; CCAAT/Enhancer Binding Protein (C/EBP), Beta; IL6DBP; TCF-5; LIP; LAP; Liver-Enriched Transcriptional Activator Protein; Interleukin 6-Dependent DNA-Binding Protein; Liver-Enriched Inhibitory Protein; Nuclear Factor

Background

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions.

Anti-CEBPB rAb Products

Our anti-CEBPB recombinant antibodies are designed with high specificity, rigorously validated to detect various isoforms of the CEBPB protein. This level of precision is critical for the accurate study of its multifaceted functions. Optimized for challenging applications, including Western Blot, IHC, and Chromatin Immunoprecipitation (ChIP), our rAbs deliver clear, reliable results to power your research.

Table 1. Featured anti-CEBPB recombinant antibody products at Creative Biolabs.

Customer Reviews

rAb Production

Creative Biolabs is at the forefront of advanced production technologies to support leading-edge oncology research. The anti-CEBPB recombinant antibodies are expressed in highly optimized systems to ensure that they accurately recognize the native protein and are thus a highly specific and active tool for your research.

Featured Anti-CEBPB Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-CEBPB recombinant antibody production.

Fig.2 Gram-scale anti-CEBPB recombinant antibody production.

rAb Modalities

Creative Biolabs is committed to enabling scientific advances through flexible antibody solutions. The anti-CEBPB recombinant antibodies are available in a variety of customizable modalities to meet a wide range of experimental needs, empowering researchers worldwide to study this critical transcription factor.

Fig.3 Full-length anti-CEBPB recombinant antibody production and modalities.

Explore the critical roles of CEBPB in gene regulation with the exceptional quality of Creative Biolabs’ recombinant antibodies. Our portfolio is characterized by its high specificity and thorough validation, ensuring the ideal tools for your research into cancer and inflammation. Discover excellence with Creative Biolabs – where quality drives discovery. Contact our experts today.