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CENPP
CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008]
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Suprabasal keratinocytes, Microglial cells, Oligodendrocytes, Excitatory neurons, Inhibitory neurons, Basal keratinocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and CENPU.
More Types Infomation
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- Species Reactivity: Human
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.