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CLCA1

Anti-CLCA1 Products
- Recombinant Mouse Anti-Human CLCA1 Antibody (MOB-1103MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P, WB, IP
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.
Protein class
Transporters
Predicted location
Secreted
Single cell type specificity
Cell type enriched (Intestinal goblet cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BEWO, NB-4, RPMI-8226, SH-SY5Y, U-2197)
Molecular function
Hydrolase, Metalloprotease, Protease
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